Natale, Giuseppina
Calabrese, Valeria
Marino, Gioia
Campanelli, Federica
Urciuolo, Federica
de Iure, Antonio
Ghiglieri, Veronica
Calabresi, Paolo
Bossola, Maurizio http://orcid.org/0000-0003-1627-0235
Picconi, Barbara http://orcid.org/0000-0001-6020-1021
Article History
Received: 11 March 2021
Revised: 10 September 2021
Accepted: 27 September 2021
First Online: 16 October 2021
Competing interests
: PC received/receives research support, speaker honoraria, and support to attend national and international conferences (not related to the present study) from Abbvie, Bial, Bayer Schering, Biogen-Dompè, Biogen-Idec, Eisai, Lilly, Lundbeck, Lusofarmaco, Merck-Serono, Novartis, Sanofi-Genzyme, Teva, UCB Pharma, Zambon. The other authors reported no funding from any institution, including personal relationships, interests, grants, employment, affiliations, patents, inventions, honoraria, consultancies, royalties, stock options/ownership, or expert testimony for the last 12 months biomedical financial interests or potential conflicts of interest. All other authors have nothing to declare.
: The study was conducted according to the guidelines of the Declaration of Helsinki and approved by the Institutional Ethics Committee of Università Cattolica del Sacro Cuore (protocol code 18195/16 - 23597/16 - of 7/13/2016). All procedures on animals were performed in strict accordance with a protocol approved by the Animal Care and Use Committee at the Italian Ministry of Health and European Communities Council Directive of September 2010 (2010/63/E).