Kong, Chang http://orcid.org/0000-0003-2363-6717
Ni, Xuqing http://orcid.org/0000-0002-2118-1918
Wang, Yixiu http://orcid.org/0000-0002-4498-1950
Zhang, Anqi http://orcid.org/0000-0002-7399-0805
Zhang, Yingying http://orcid.org/0000-0001-7717-5237
Lin, Feihong http://orcid.org/0000-0001-5914-295X
Li, Shan http://orcid.org/0000-0002-6737-5873
Lv, Ya http://orcid.org/0000-0002-8313-9846
Zhu, Jingwen http://orcid.org/0000-0001-7802-0544
Yao, Xinyu http://orcid.org/0000-0002-9805-5485
Dai, Qinxue http://orcid.org/0000-0002-2516-5798
Mo, Yunchang http://orcid.org/0000-0001-8671-6322
Wang, Junlu http://orcid.org/0000-0002-7486-2207
Funding for this research was provided by:
Wenzhou Municipal Science and Technology Bureau (Y20190202, 2018ZY003, Y20190108)
National Natural Science Foundation of China (81704180)
Natural Science Foundation of Zhejiang Province (LY19H290008)
Article History
Received: 11 August 2021
Revised: 3 February 2022
Accepted: 16 March 2022
First Online: 9 April 2022
Competing interests
: The authors declare no competing interests.
: On the ethics review, human study (ChiCTR-INR-2100051426) was accepted by the Ethics Committee of the First Affiliated Hospital of Wenzhou Medical University and was conformed to the protocols in the Declaration of Helsinki and in the Federal Policy for the Protection of Human Subjects, with informed consent provided by each participated patient. Each animal assay, aiming to bring the mouse killing to the minimum, was accepted by the Animal Experimentation Ethics Committee (Approval Ethical Inspection ID: wydw2019-0559).