Groenewoud, Arwin
Yin, Jie
Gelmi, Maria Chiara
Alsafadi, Samar http://orcid.org/0000-0002-0060-1346
Nemati, Fariba
Decaudin, Didier
Roman-Roman, Sergio
Kalirai, Helen
Coupland, Sarah E.
Jochemsen, Aart G. http://orcid.org/0000-0002-0570-7967
Jager, Martine J. http://orcid.org/0000-0003-2261-3820
Engel, Felix B. http://orcid.org/0000-0003-2605-3429
Snaar-Jagalska, B. E.
Funding for this research was provided by:
EC | Horizon 2020 Framework Programme (667787, 667787)
Article History
Received: 3 November 2022
Revised: 24 March 2023
Accepted: 24 April 2023
First Online: 16 June 2023
Competing interests
: The authors declare no competing interests.
: The analysis was approved by the METC of the LUMC (B14.003/SH/sh Approval Biobank OOG-2 “Oogtumoren (of een verdenking hierop)”, protocol Uveamelanoom-lab B20.026, approval June 2020). Fresh material was used for spheroids under METC protocol UM CURE 2020: Prospective collection: new treatment options for metastatic uveal melanoma (NL57166.058.16). The research adhered to Dutch law and the tenets of the Declaration of Helsinki (World Medical Association of Declaration 2013; ethical principles for medical research involving human subjects). Each patient had signed an informed consent. All animal experiments were approved by Animal Experiments Committee (Dier Experimenten Commissie, D.E.C.) under license AVD1060020172410. Animals were maintained in accordance with local guidelines using standard protocols (ExternalRef removed).