Cirillo, Francesca
Talia, Marianna
Santolla, Maria Francesca http://orcid.org/0000-0002-4838-5953
Pellegrino, Michele
Scordamaglia, Domenica
Spinelli, Asia
De Rosis, Salvatore
Giordano, Francesca
Muglia, Lucia
Zicarelli, Azzurra
Di Dio, Marika
Rigiracciolo, Damiano Cosimo
Miglietta, Anna Maria
Filippelli, Gianfranco
De Francesco, Ernestina Marianna
Belfiore, Antonino http://orcid.org/0000-0002-6181-4193
Lappano, Rosamaria
Maggiolini, Marcello http://orcid.org/0000-0002-7485-854X
Funding for this research was provided by:
Associazione Italiana per la Ricerca sul Cancro (21322, 21651, 23369, 27386)
Ministero della Salute (RF-2019-12368937, RF-2019-12368937, RF-2019-12368937)
Article History
Received: 10 May 2023
Revised: 28 June 2023
Accepted: 18 September 2023
First Online: 26 September 2023
Competing interests
: The authors declare no competing interests.
: All procedures conformed to the Helsinki Declaration for the research on humans. Signed informed consent was obtained from all patients and the experimental research has been performed with the ethical approval provided by the “Comitato Etico Regione Calabria, Cosenza, Italy” (approval code: 500/2022). Animal care, death and experiments were done in accordance to the principle of the 3Rs and according to Italian law (D.L. 26/2014), the Guide for Care and Use of Laboratory Animals published by the US National Institutes of Health (2011), and the Directive 2010/63/EU of the European Parliament on the protection of animals used for Scientific research. The animal research project was approved by the Italian Ministry of Health, Rome (authorization n. 706/2018-PR). All the experimental procedures were approved by the Bioethics Committee on Animal Experiments (OPBA) of the Department of Biology, Ecology and Earth Sciences, University of Calabria.