Funding for this research was provided by:
Foundation for the National Institutes of Health (R21AI22922)
Text and Data Mining valid from 2020-05-07
Received: 7 January 2020
Accepted: 20 March 2020
First Online: 7 May 2020
: The authors declare no competing interests.
: The housing and handling of mice follow guidelines established by the Johns Hopkins Medical Institutions Animal Care and Use Committee and the National Institutes of Health. The Oncology Center Animal Facility has full-time veterinary support through the Department of Comparative Medicine. Animals are monitored daily for infection and other illnesses by trained animal technicians. The criteria include infection, failure to thrive, perceived pain, respiratory distress, etc. Research support services include training classes, and the capacity for full postmortem analysis is available on request. Only trained laboratory personnel and animal technicians were allowed to handle laboratory animals. All individuals handling mice were registered to protocols of the Johns Hopkins Animal Care and Use Committee.