Gonzaga-Jauregui, Claudia http://orcid.org/0000-0002-4667-3679
,
Yesil, Gozde
Nistala, Harikiran http://orcid.org/0000-0003-4928-7527
Gezdirici, Alper http://orcid.org/0000-0002-2432-9279
Bayram, Yavuz
Nannuru, Kalyan C.
Pehlivan, Davut
Yuan, Bo
Jimenez, Johanna
Sahin, Yavuz http://orcid.org/0000-0002-7831-067X
Paine, Ingrid S.
Akdemir, Zeynep Coban
Rajamani, Saathyaki
Staples, Jeffrey
Dronzek, John
Howell, Kristen
Fatih, Jawid M.
Smaldone, Silvia
Schlesinger, Alan E.
RamÃrez, Norman
Cornier, Alberto S.
Kelly, Melissa A.
Haber, Robert
Chim, Shek Man http://orcid.org/0000-0002-5116-8394
Nieman, Kristy
Wu, Nan
Walls, Johnathon
Poueymirou, William
Siao, Chia-Jen
Sutton, V. Reid
Williams, Marc S. http://orcid.org/0000-0001-6165-8701
Posey, Jennifer E.
Gibbs, Richard A.
Carlo, Simon
Tegay, David H.
Economides, Aris N. http://orcid.org/0000-0002-6508-8942
Lupski, James R.
Article History
Received: 27 November 2019
Revised: 31 March 2020
Accepted: 7 April 2020
First Online: 6 May 2020
Compliance with ethical standards
:
: CG-J, HN, KN, JJ, JD, SR, JS, SS, JW, WP, C-JS, and AE are full time employees of the Regeneron Genetics Center or Regeneron Pharmaceuticals Inc. and receive stock options as part of compensation. JRL is a paid consultant for Regeneron Pharmaceuticals Inc., Novartis, and has stock ownership in 23andMe and is a co-inventor on multiple United States and European patents related to molecular diagnostics for inherited neuropathies, eye diseases, and bacterial genomic fingerprinting. Baylor College of Medicine (BCM) and Miraca Holdings Inc. have formed a joint venture, Baylor Genetics (BG), with shared ownership and governance of the BG diagnostic laboratory, which performs clinical exome sequencing (cES). RAG and JRL were involved in setting up cES for BG and have served on their Scientific Advisory Board. The remaining authors declare no conflict of interest.