Glessner, Joseph T. http://orcid.org/0000-0001-5131-2811
Li, Jin
Liu, Yichuan
Khan, Munir
Chang, Xiao
Sleiman, Patrick M. A.
Hakonarson, Hakon http://orcid.org/0000-0003-2814-7461
Funding for this research was provided by:
U.S. Department of Health & Human Services | NIH | National Human Genome Research Institute (U01-HG006830, U01-HG006830)
U.S. Department of Health & Human Services | NIH | National Human Genome Research Institute
Article History
Received: 7 December 2021
Revised: 1 October 2022
Accepted: 14 October 2022
First Online: 1 November 2022
Ethical approval
: All subjects were recruited through IRB-approved protocols. Participants enrolled in various studies and completed a broad informed consent, including consent for prospective analyses of EHRs. Confidentiality is guarded to address issues of privacy and insurability. Each subject is assigned a study number upon recruitment, using complex algorithms to remove personal identification. Encrypted patient data is integrated into the lab’s custom phenotype browser, where it can be coupled with genotyping and sequencing data.
: The authors declare no competing interests. Unrelated to this manuscript, we disclose that HH and CHOP own stock in Aevi Genomic Medicine.