Caraffi, Stefano Giuseppe http://orcid.org/0000-0002-5033-7854
van der Laan, Liselot http://orcid.org/0000-0002-7800-8665
Rooney, Kathleen http://orcid.org/0000-0002-7871-8982
Trajkova, Slavica
Zuntini, Roberta
Relator, Raissa
Haghshenas, Sadegheh
Levy, Michael A.
Baldo, Chiara
Mandrile, Giorgia http://orcid.org/0000-0003-0849-2225
Lauzon, Carolyn
Cordelli, Duccio Maria
Ivanovski, Ivan
Fetta, Anna
Sukarova, Elena http://orcid.org/0000-0001-9702-3994
Brusco, Alfredo http://orcid.org/0000-0002-8318-7231
Pavinato, Lisa http://orcid.org/0000-0002-7630-8365
Pullano, Verdiana http://orcid.org/0000-0002-0409-9832
Zollino, Marcella http://orcid.org/0000-0003-4871-9519
McConkey, Haley
Tartaglia, Marco http://orcid.org/0000-0001-7736-9672
Ferrero, Giovanni Battista
Sadikovic, Bekim http://orcid.org/0000-0001-6363-0016
Garavelli, Livia http://orcid.org/0000-0002-7684-3982
Funding for this research was provided by:
Ministero dell'Istruzione, dell'Università e della Ricerca (MNESYS (PE0000006), 20203P8C3X, FOE 2020)
Ministero dell'Istruzione, dell'Università e della Ricerca
Ministero dell'Istruzione, dell'Università e della Ricerca
Ministero della Salute (RCR-2022-23682289, PNRR-MR1-2022-12376811)
Ontario Genomics Institute (OGI-188)
Article History
Received: 24 October 2023
Revised: 10 January 2024
Accepted: 18 January 2024
First Online: 13 February 2024
Competing interests
: BS is a shareholder in EpiSign Inc., involved in commercialization of EpiSign technology.
: The study was conducted in accordance with the regulations of the Western University Research Ethics Board (REB116108, and REB106302), with the Declaration of Helsinki of 1996, and with the European Regulations on personal data protection [EU 2016/679]. The study was approved by the Research Ethics Committee of Area Vasta Emilia Nord (CE-AVEN 06/09/2022, 529/2022/TESS/AUSLRE, protocol no. 2022/0112043) and by the competent local institutional review boards. Written informed consent to publish clinical and genetic information was obtained from the parents/legal guardians of the individuals whose samples were included in this study.