Received: 20 June 2018
Revised: 12 November 2018
Accepted: 22 December 2018
First Online: 6 February 2019
Compliance with ethical standards
: Investigator-led trial. SJT—advisory board work for Novartis, Bayer; Optos, has received travel grants from Novartis, Bayer and Allergan; Honoraria for presentations from Novartis, Bayer. DB—involved in research from Bayer and Novartis. GM—has received research and travel grants from Novartis and Bayer. AC—has received educational travel grants from Novartis & Bayer. SS—has received travel fees, honorarium for advisory board and research grants from Bayer, Allergan, Novartis and Roche, Boehringer Ingleheim. SS has received honorarium for advisory board from Optos Plc and Heidelberg Engineering. NVC—at the time of the trial he worked as an ophthalmologist at the Oxford Eye Hospital, now he is an employee of Boehringer Ingelheim International GmBH. HE—received travelling grants, honoraria from Novartis and participated in Board meetings. LD—advisory board work for Novartis, Bayer, Alimera and Allerga; has received travel grants from Novartis, Bayer and Allergan; Honoraria for presentations from Novartis, Bayer, Alimera.