Article History
Received: 18 February 2021
Revised: 2 August 2021
Accepted: 18 August 2021
First Online: 21 September 2021
Competing interests
: The authors declare no competing interests.
: This study was conducted with approval of the Ethics Committee of Linyi People’s Hospital and in line with the <i>Declaration of Helsinki</i>. All patients and/or legal guardians signed the informed consent documentation prior to sample collection. Animal experiments were approved by the Animal Ethics Committee of Linyi People’s Hospital. Great efforts were made to minimize the number of animals used in the experiments and their suffering.