Funding for this research was provided by:
National Institute of Neurological Disorders and Stroke (K02 NS112600)
Received: 22 October 2020
Revised: 4 February 2021
Accepted: 5 February 2021
First Online: 17 March 2021
: Informed consent for participation in this study was obtained from subjects themselves or parents of all probands in agreement with the Declaration of Helsinki, and the study was completed per protocol with local approval by the Children’s Hospital of Philadelphia (CHOP) Institutional Review Board (IRB 15-12226). All data have been de-identified.
: I.H. serves on the Scientific Advisory Board of Biogen. The other authors declare no competing interests.