Article History
Received: 20 February 2018
Accepted: 5 April 2018
First Online: 15 May 2018
Competing interests
: A provisional patent (Composition and Methods for Multiplexed Genome Editing and Screening, US provisional patent no. 62/660,467, filed April 20, 2018) has been filed by R.D.C. and S.C. related to sequential mutagenesis in this study. The remaining author declares no competing interests.