Text and Data Mining valid from 2019-01-02
Received: 26 July 2018
Accepted: 29 November 2018
First Online: 2 January 2019
: C.B., P.H., U.B., D.P., H.P. and M.W. are employees and therefore shareholders of AstraZeneca, however, they have no financial or intellectual property rights to the structures presented in this manuscript which were transferred to the LSTM, a charitable organisation. The remaining authors declare no competing interests.