Arnold, Nadine D. http://orcid.org/0000-0002-4317-5738
Pickworth, Josephine A. http://orcid.org/0000-0002-7199-364X
West, Laura E. http://orcid.org/0000-0003-2953-2521
Dawson, Sarah
Carvalho, Joana A.
Casbolt, Helen
Braithwaite, Adam T. http://orcid.org/0000-0003-3228-2172
Iremonger, James http://orcid.org/0000-0003-3953-8812
Renshall, Lewis
Germaschewski, Volker
McCourt, Matthew
Bland-Ward, Philip
Kowash, Hager http://orcid.org/0000-0003-4732-470X
Hameed, Abdul G. http://orcid.org/0000-0002-2128-2081
Rothman, Alexander M. K. http://orcid.org/0000-0002-7847-4500
Frid, Maria G.
Roger Thompson, A. A. http://orcid.org/0000-0002-0717-4551
Evans, Holly R. http://orcid.org/0000-0001-6712-2481
Southwood, Mark
Morrell, Nicholas W. http://orcid.org/0000-0001-5700-9792
Crossman, David C. http://orcid.org/0000-0003-4762-8623
Whyte, Moira K. B. http://orcid.org/0000-0001-7788-1852
Stenmark, Kurt R. http://orcid.org/0000-0001-6918-6411
Newman, Christopher M.
Kiely, David G.
Francis, Sheila E. http://orcid.org/0000-0001-6552-0339
Lawrie, Allan http://orcid.org/0000-0003-4192-9505
Funding for this research was provided by:
RCUK | Medical Research Council (G0800318, MC/PC12022, MR/L023040/1, MR/K002406/1)
British Heart Foundation (FS/13/48/30453, FS/18/52/33808, FS/08/061/25740, FS/18/13/33281)
Wellcome Trust (206632/Z/17/Z)
Article History
Received: 21 September 2017
Accepted: 23 October 2019
First Online: 15 November 2019
Competing interests
: A.L./The University of Sheffield has been granted intellectual property around the area of targeting OPG for the treatment of PAH (GB2510524 / US9334327 / JP2014532637) and is a founding Director of PH Therapeutics Ltd, a University of Sheffield Spin-out company. J.C., V.G., M.M. and P.B.-W. are employees of Kymab Ltd and hold share options in the company. Kymab has filed intellectual property (GB1701416.8) around the characteristics of a therapeutic human anti-osteoprotegerin antibody with A.L. named as an inventor. The remaining authors declare no competing interests.