Harris, Sarah E. http://orcid.org/0000-0002-4941-5106
Cox, Simon R. http://orcid.org/0000-0003-4036-3642
Bell, Steven http://orcid.org/0000-0001-6774-3149
Marioni, Riccardo E.
Prins, Bram P.
Pattie, Alison
Corley, Janie
Muñoz Maniega, Susana
Valdés Hernández, Maria
Morris, Zoe
John, Sally
Bronson, Paola G.
Tucker-Drob, Elliot M.
Starr, John M.
Bastin, Mark E.
Wardlaw, Joanna M. http://orcid.org/0000-0002-9812-6642
Butterworth, Adam S.
Deary, Ian J.
Funding for this research was provided by:
U.S. Department of Health & Human Services | National Institutes of Health (R01AG054628, R01AG054628)
RCUK | Medical Research Council (G0701120, G1001245, MR/M013111/1, MR/R024065/1, MR/L003120/1, G0701120, G1001245, MR/M013111/1, MR/R024065/1, MR/K026992/1)
British Heart Foundation (SP/09/002, RG/13/13/30194, RG/18/13/33946)
NIHR Blood and Transplant Research Unit in Donor Health and Genomics
Article History
Received: 14 June 2019
Accepted: 19 December 2019
First Online: 10 February 2020
Competing interests
: The authors declare no competing interests.
: Ethics permission for the LBC1936 was obtained from the Scotland A Research Ethics Committee (07/MRE00/58). Ethics permission for the LBC1921 was obtained from the Lothian Research Ethics Committee (1702/98/4/183). The INTERVAL trial has received ethics committee approval from the National Research Ethics Service Committee East of England- (REC 11/EE/0538). All persons gave their informed consent prior to their inclusion in the study.