Mathyer, Mary Elizabeth http://orcid.org/0000-0003-4725-7439
Brettmann, Erin A. http://orcid.org/0000-0001-8603-0670
Schmidt, Alina D.
Goodwin, Zane A.
Oh, Inez Y.
Quiggle, Ashley M.
Tycksen, Eric
Ramakrishnan, Natasha
Matkovich, Scot J.
Guttman-Yassky, Emma http://orcid.org/0000-0002-9363-324X
Edwards, John R.
de Guzman Strong, Cristina http://orcid.org/0000-0001-8540-9611
Funding for this research was provided by:
U.S. Department of Health & Human Services | NIH | National Institute of General Medical Sciences (T32GM007067, R25GM103757, T32GM007067, R25GM103757)
Society of Investigative Dermatology/Sun Pharma Research Innovation Fellowship
U.S. Department of Health & Human Services | NIH | National Institute of General Medical Sciences
U.S. Department of Health & Human Services | NIH | National Human Genome Research Institute (T32HG000045, T32HG000045, T32HG000045)
U.S. Department of Health & Human Services | NIH | National Human Genome Research Institute
U.S. Department of Health & Human Services | NIH | U.S. National Library of Medicine (R01LM013096)
U.S. Department of Health & Human Services | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases (R01AR065523, R56075427)
U.S. Department of Health & Human Services | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases
U.S. Department of Health & Human Services | NIH | National Cancer Institute (P30CA91842)
U.S. Department of Health & Human Services | NIH | National Center for Research Resources (UL1TR002345)
U.S. Department of Health & Human Services | NIH | National Human Genome Research Institute
U.S. Department of Health & Human Services | NIH | National Institute of General Medical Sciences
U.S. Department of Health & Human Services | NIH | National Institute of General Medical Sciences
Article History
Received: 10 October 2019
Accepted: 30 March 2021
First Online: 7 May 2021
Competing interests
: C.dG.S., M.E.M., E.A.B., Z.A.G., and I.Y.O. are inventors on provisional patent application 63/090,801 submitted by Washington University in St. Louis that covers the compositions and methods for treating skin diseases, disorders, or conditions. C.dG.S. is the founder of Evoly Skin, LLC that is developing new technologies to improve the skin barrier. E.G.Y. is an employee of Mount Sinai and has received research funds (grants paid to the institution) from Abbvie, Almirall, Amgen, AnaptysBio, Asana Biosciences, AstraZeneca, Boerhinger-Ingelhiem, Celgene, Dermavant, DS Biopharma, Eli Lilly, Galderma,Glenmark/Ichnos Sciences, Innovaderm, Janssen, Kiniksa, Kyowa Kirin, Leo Pharma, Novan, Novartis, Pfizer, Ralexar, Regeneron Pharmaceuticals, Inc., Sienna Biopharma, UCB, and Union Therapeutics/Antibiotx; and is a consultant for Abbvie, Aditum Bio, Almirall, Alpine, Amgen, Arena, Asana Biosciences, AstraZeneca, Bluefin Biomedicine, Boerhinger-Ingelhiem, Boston Pharmaceuticals, Botanix, Bristol-Meyers Squibb, Cara Therapeutics, Celgene, Clinical Outcome Solutions, DBV, Dermavant, Dermira, Douglas Pharmaceutical, DS Biopharma, Eli Lilly, EMD Serono, Evelo Bioscience, Evidera, FIDE, Galderma, GSK, Haus Bioceuticals, Ichnos Sciences, Incyte, Kyowa Kirin, Larrk Bio, Leo Pharma, Medicxi, Medscape, Neuralstem, Noble Insights, Novan, Novartis, Okava Pharmaceuticals, Pandion Therapeutics, Pfizer, Principia Biopharma, RAPT Therapeutics, Realm, Regeneron Pharmaceuticals, Inc., Sanofi, SATO Pharmaceutical, Sienna Biopharma, Seanegy Dermatology, Seelos Therapeutics, Serpin Pharma, Siolta Therapeutics, Sonoma Biotherapeutics, Sun Pharma, Target PharmaSolutions, Union Therapeutics, Vanda Pharmaceuticals, Ventyx Biosciences, and Vimalan. Consultant for Abbvie, Aditum Bio, Almirall, Amgen, Asana Biosciences, AstraZeneca, Boerhinger-Ingelhiem, Cara Therapeutics, Celgene, Concert, DBV, Dermira, DS Biopharma, Eli Lilly, EMD Serono, Galderma, Ichnos Sciences, Incyte Kyowa Kirin, Leo Pharma, Pandion Therapeutics, Pfizer, RAPT Therapeutics, Regeneron Pharmaceuticals, Inc., Sanofi, Sienna Biopharma, Target PharmaSolutions, and Union Therapeutics. The other authors declare no competing interests.