Yang, Jin http://orcid.org/0000-0001-6489-3926
Lee, Jihwan http://orcid.org/0000-0002-5426-2765
Land, Michelle A.
Lai, Shujuan
Igoshin, Oleg A. http://orcid.org/0000-0002-1449-4772
St-Pierre, François http://orcid.org/0000-0001-8618-4135
Article History
Received: 14 July 2020
Accepted: 19 May 2021
First Online: 5 July 2021
Competing interests
: The authors declare the following competing interests: on May 12, 2021, Baylor College of Medicine and William Marsch Rice University filed a provisional patent application (#63187704) based on this work. F.S.-P., J.Y., and O.A.I. are the inventors, and all authors are contributors. The application covers most of the work described in the manuscript, including systems, compositions, and methods for regulating gene expression, including in a manner that allows for enhanced control of copy-number variation at both the population and single-cell levels compared with known systems.