Routhu, Nanda Kishore
Cheedarla, Narayanaiah
Bollimpelli, Venkata Satish
Gangadhara, Sailaja
Edara, Venkata Viswanadh http://orcid.org/0000-0001-9321-7839
Lai, Lilin
Sahoo, Anusmita
Shiferaw, Ayalnesh
Styles, Tiffany M.
Floyd, Katharine http://orcid.org/0000-0002-0866-6961
Fischinger, Stephanie http://orcid.org/0000-0003-2307-3379
Atyeo, Caroline http://orcid.org/0000-0002-7489-0232
Shin, Sally A. http://orcid.org/0000-0002-9306-2264
Gumber, Sanjeev
Kirejczyk, Shannon
Dinnon, Kenneth H. III
Shi, Pei-Yong http://orcid.org/0000-0001-5553-1616
Menachery, Vineet D. http://orcid.org/0000-0001-8803-7606
Tomai, Mark
Fox, Christopher B.
Alter, Galit http://orcid.org/0000-0002-7680-9215
Vanderford, Thomas H.
Gralinski, Lisa http://orcid.org/0000-0003-1374-8002
Suthar, Mehul S.
Amara, Rama Rao http://orcid.org/0000-0002-6309-6797
Funding for this research was provided by:
U.S. Department of Health & Human Services | National Institutes of Health (RO1 AI148378-01S1, 2166)
U.S. Department of Health & Human Services | National Institutes of Health
U.S. Department of Health & Human Services | NIH | National Center for Research Resources (P51 OD011132)
Article History
Received: 23 February 2021
Accepted: 26 May 2021
First Online: 11 June 2021
Competing interests
: R.R.A., N.C. and N.K.R are co-inventors of RBD trimer vaccine technology. Emory university filed a patent on this technology. C.B.F is an inventor on a patent application of the 3M-052-Alum formulation. All other authors declare no competing interests.
: Mice and rhesus macaques were housed at the Yerkes National Primate Research Center and animal experiments were approved by the Emory University Institutional Animal Care and Use Committee (IACUC) using protocols PROTO201700014 and PROTO202000057. All animal experiments were carried out in accordance to USDA regulations and recommendations derived from the Guide for the Care and Use of Laboratory Animals. Mice were shipped to the University of North Carolina (UNC) at Chapel Hill and performed SARS-CoV-2 (MA10) challenge experiments using IACUC protocol 20-114.