Funding for this research was provided by:
Farmer Family Foundation
Received: 18 March 2020
Accepted: 4 August 2021
First Online: 26 August 2021
: For the human tissue studies, the study protocol was ethically approved by the institutional review board at the Van Andel Research Institute (IRB #15025). For the gut inflammation mouse model, the animal experiments were endorsed by a Roche internal review board and approved by the local animal welfare authorities in Canton Basel-Stadt, Basel, Switzerland. The experiment using rAAV vectors in mice was performed in accordance and with ethical approval of the Michigan State University Institutional Animal Care & Use Committee guidelines (AUF 08-16-148-00).
: N.M., R.L., C.R., J.S.P., P.M., and M.B. are or were full-time employees at Roche and they may additionally hold Roche stock/stock options. No other authors have conflicts of interest.