Gordevicius, Juozas http://orcid.org/0000-0003-3190-6721
Li, Peipei
Marshall, Lee L.
Killinger, Bryan A.
Lang, Sean http://orcid.org/0000-0002-7115-1506
Ensink, Elizabeth http://orcid.org/0000-0001-7309-9943
Kuhn, Nathan C.
Cui, Wei
Maroof, Nazia
Lauria, Roberta
Rueb, Christina
Siebourg-Polster, Juliane
Maliver, Pierre
Lamp, Jared
Vega, Irving
Manfredsson, Fredric P. http://orcid.org/0000-0001-5802-5487
Britschgi, Markus http://orcid.org/0000-0001-6151-4257
Labrie, Viviane http://orcid.org/0000-0003-1037-1967
Funding for this research was provided by:
Farmer Family Foundation
Article History
Received: 18 March 2020
Accepted: 4 August 2021
First Online: 26 August 2021
Ethics approval
: For the human tissue studies, the study protocol was ethically approved by the institutional review board at the Van Andel Research Institute (IRB #15025). For the gut inflammation mouse model, the animal experiments were endorsed by a Roche internal review board and approved by the local animal welfare authorities in Canton Basel-Stadt, Basel, Switzerland. The experiment using rAAV vectors in mice was performed in accordance and with ethical approval of the Michigan State University Institutional Animal Care & Use Committee guidelines (AUF 08-16-148-00).
: N.M., R.L., C.R., J.S.P., P.M., and M.B. are or were full-time employees at Roche and they may additionally hold Roche stock/stock options. No other authors have conflicts of interest.