Tsagkaraki, Emmanouela http://orcid.org/0000-0001-7754-8945
Nicoloro, Sarah M. http://orcid.org/0000-0002-8638-4556
DeSouza, Tiffany
Solivan-Rivera, Javier
Desai, Anand
Lifshitz, Lawrence M.
Shen, Yuefei
Kelly, Mark http://orcid.org/0000-0001-9018-594X
Guilherme, Adilson http://orcid.org/0000-0003-0535-5911
Henriques, Felipe http://orcid.org/0000-0002-9245-7141
Amrani, Nadia
Ibraheim, Raed http://orcid.org/0000-0002-0961-7299
Rodriguez, Tomas C. http://orcid.org/0000-0002-8724-5427
Luk, Kevin
Maitland, Stacy
Friedline, Randall H. http://orcid.org/0000-0003-0894-448X
Tauer, Lauren http://orcid.org/0000-0002-2315-1050
Hu, Xiaodi
Kim, Jason K. http://orcid.org/0000-0002-7185-042X
Wolfe, Scot A. http://orcid.org/0000-0002-7042-201X
Sontheimer, Erik J. http://orcid.org/0000-0002-0881-0310
Corvera, Silvia http://orcid.org/0000-0002-0009-4129
Czech, Michael P. http://orcid.org/0000-0003-4075-7350
Funding for this research was provided by:
U.S. Department of Defense (W81XWH-18-1-0397, W81XWH-18-1-0398)
Isadore and Fannie Foxman Chair in Medical Science
American Diabetes Association (1-19-PMF-035)
the Endowed Professorship in Diabetes Research Chair
Article History
Received: 28 October 2020
Accepted: 8 November 2021
First Online: 26 November 2021
Competing interests
: The authors declare the following competing Interests: M.P.C. and A.J.G. are inventors of granted US Patent #8,519,118, “RIP140 regulation of glucose transport”, and of granted US Patent #8,093,223, “RIP140 regulation of diabetes”, related to data in this paper on Nrip1/RIP140-depleted mouse and human adipocytes. SC is inventor on granted US Patent #10,093,902, “Human adipose tissue white and brown-on-white progenitors for reconstructive and metabolic therapies”, related to data in this paper on human adipose progenitors and human adipocytes. M.P.C., S.C., E.T., and S.M.N. are inventors of pending US Patent application #63/089,955, “Targeting Nrip1 to Alleviate Metabolic Disease”, related to CRISPR-based depletion of Nrip1 in mouse and human adipocytes in this paper. The University of Massachusetts is the grantee or potential grantee of all of the above. MPC and SC declare that they are bound by confidentiality agreements that prevent them from disclosing a potentially competing interest in this work. E.J.S. is a co-founder and scientific advisor of Intellia Therapeutics. The remaining authors declare no competing interests.