Zeve, Daniel
Stas, Eric
de Sousa Casal, Joshua http://orcid.org/0000-0003-2006-3992
Mannam, Prabhath
Qi, Wanshu
Yin, Xiaolei
Dubois, Sarah
Shah, Manasvi S.
Syverson, Erin P.
Hafner, Sophie
Karp, Jeffrey M.
Carlone, Diana L. http://orcid.org/0000-0001-6935-0189
Ordovas-Montanes, Jose http://orcid.org/0000-0001-5444-5601
Breault, David T. http://orcid.org/0000-0002-0402-4857
Funding for this research was provided by:
U.S. Department of Health & Human Services | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (T32DK769937, K12DK09472109, P30 DK034854, DK119488, DK034854)
U.S. Department of Health & Human Services | NIH | National Institute of Diabetes and Digestive and Kidney Diseases
JDRF (3-APF-2020-929-A-N)
Pediatric Endocrine Society
U.S. Department of Health & Human Services | National Institutes of Health (HL095722, UC4DK104165)
U.S. Department of Health & Human Services | National Institutes of Health
U.S. Department of Health & Human Services | NIH | National Institute of Diabetes and Digestive and Kidney Diseases
Damon Runyon Cancer Research Foundation (DRG-2274-16)
AGA Research Foundation (AGA2020-13-01)
Richard and Susan Smith Family Foundation
New York Stem Cell Foundation
Food Allergy Science Initiative
U.S. Department of Health & Human Services | NIH | National Institute of Diabetes and Digestive and Kidney Diseases
U.S. Department of Health & Human Services | NIH | National Institute of Diabetes and Digestive and Kidney Diseases
The Adolph Coors Foundation
Article History
Received: 28 August 2020
Accepted: 16 December 2021
First Online: 11 January 2022
Competing interests
: The author J.M.K. holds equity in Frequency Therapeutics, a company that has an option to license IP generated by J.M.K. and that may benefit financially if the IP is licensed and further validated. Also, J.M.K. has been a paid consultant and/or equity holder for multiple companies (listed here ExternalRef removed). The interests of J.M.K. was reviewed and are subject to a management plan overseen by their institutions in accordance with their conflict-of-interest policies. J.O.M. reports compensation for consulting services with Cellarity and Hovione. The remaining authors declare no competing interests. A patent was filed by D.Z. and D.T.B covering compositions and methods for regulating enteroendocrine cell differentiation and uses thereof as described in the manuscript.