Wang, Qiwei http://orcid.org/0000-0003-3897-2529
Bergholz, Johann S. http://orcid.org/0000-0003-4609-8448
Ding, Liya
Lin, Ziying
Kabraji, Sheheryar K. http://orcid.org/0000-0002-5315-7103
Hughes, Melissa E.
He, Xiadi
Xie, Shaozhen
Jiang, Tao
Wang, Weihua
Zoeller, Jason J.
Kim, Hye-Jung http://orcid.org/0000-0001-5595-4264
Roberts, Thomas M.
Konstantinopoulos, Panagiotis A. http://orcid.org/0000-0002-1032-1479
Matulonis, Ursula A.
Dillon, Deborah A.
Winer, Eric P.
Lin, Nancy U.
Zhao, Jean J. http://orcid.org/0000-0002-4561-5688
Funding for this research was provided by:
U.S. Department of Health & Human Services | National Institutes of Health (P50CA168504, P50CA165962, R35CA210057)
U.S. Department of Health & Human Services | National Institutes of Health
U.S. Department of Defense (BC171657)
U.S. Department of Health & Human Services | National Institutes of Health
Article History
Received: 16 August 2021
Accepted: 6 May 2022
First Online: 31 May 2022
Competing interests
: Q.W., L.D., H.-J.K., and J.J. Zhao are co-inventors of the patent: Cancer vaccine compositions and methods for using same to treat cancer (DFCI 2409.001; DFS-203.60). Q.W., L.D., and J.J. Zhao are co-inventors of the patent: Methods of treating cancers using STING agonists (DFCI 2947.P01US; DFS-310.60). Q.W. is a scientific consultant for Crimson Biopharm Inc. J.S.B. is a scientific consultant for Geode Therapeutics Inc. J.J. Zoeller is currently an employee at AstraZeneca. T.M.R. is co-founder of Crimson Biopharm Inc. and Geode Therapeutics Inc., and a member of the SAB for Shiftbio and K2B Therapeutics. P.A.K. has served on the advisory boards of Vertex, Pfizer, Merck, and AstraZeneca. U.A.M. has served on the advisory boards of 2X Oncology, Fujifilm, Immunogen, Mersana, Geneos, and Merck. D.A.D. is on the advisory board for Oncology Analytics, Inc. and consults for Novartis. N.U.L. has received research funding (to institution) from AstraZeneca, Genentech, Olema Pharmaceuticals, Pfizer, Seattle Genetics, Merck, and Zion Pharmaceuticals and has received honoraria for consulting/advisory board for Artera Inc., Aleta BioPharma, Affinia Therapeutics, AstraZeneca, Daiichi Sankyo, Denali Therapeutics, Puma, Prelude Therapeutics and Voyager Therapeutics. J.J. Zhao is co-founder and director of Crimson Biopharm Inc. and Geode Therapeutics Inc. The remaining authors declare no competing interests.