Popat, Sanjay http://orcid.org/0000-0003-2087-4963
Liu, Stephen V.
Scheuer, Nicolas
Hsu, Grace G. http://orcid.org/0000-0001-7191-6612
Lockhart, Alexandre
Ramagopalan, Sreeram V. http://orcid.org/0000-0002-5038-0916
Griesinger, Frank
Subbiah, Vivek http://orcid.org/0000-0002-6064-6837
Funding for this research was provided by:
Roche
Article History
Received: 4 February 2022
Accepted: 25 May 2022
First Online: 17 June 2022
Competing interests
: S,P. receives honoraria from Boehringer Ingelheim, AstraZeneca, Roche, Takeda and Chugai Pharma; and provides consulting or advisory role for Boehringer Ingelheim, AstraZeneca, Roche, Takeda, Novartis, Pfizer, Bristol-Myers Squibb, MSD, Guardant Health, AbbVie and EMD Serono. Dr Liu has received research funding (to institution) from Alkermes, AstraZeneca, Bayer, Blueprint Medicines Corporation, Bristol-Myers Squibb, Corvus, Debiopharm, Elevation Oncology, Genentech, Lilly, Lycera, Merck, Merus, Pfizer, Rain Therapeutics, RAPT, and Turning Point Therapeutics; has served as consultant or advisory board member to Amgen, AstraZeneca, BeiGene, Blueprint Medicines Corporation, BMS, Catalyst, Daiichi Sankyo, G1 Therapeutics, Genentech/Roche, Guardant Health, Inivata, Janssen, Jazz Pharmaceuticals, Lilly, Merck/MSD, PharmaMar, Pfizer, Regeneron, and Takeda. Mr Scheuer reported receiving personal fees from Roche, receiving shares from Roche as an employee during the conduct of the study, and reported being an employee of and receiving shares from Novartis outside the submitted work. G.G.H. and A.L. reported receiving funding from Roche during the conduct of the study. S.V.R. reported receiving personal fees from Roche during the conduct of the study. F.G. has consulted or provided expert opinion for AMGEN, AstraZeneca, Bayer, BMS, Boehringer Ingelheim, Celgene, GSK, Lilly, MSD, Novartis, Pfizer, Roche, Siemens, and Takeda; has received fees from Amgen, AstraZeneca, Bayer, Boehringer Ingelheim, BMS, Celgene, GSK, Lilly, MSD, Novartis, Pfizer, Roche, Siemens, and Takeda; and has received funding for scientific research from Amgen, AstraZeneca, Boehringer Ingelheim, BMS, Celgene, GSK, Lilly, MSD, Novartis, Pfizer, Roche, Siemens, and Takeda. V.S. reports research funding/grant support for clinical trials from AbbVie, Agensys, Alfa-sigma, Altum, Amgen, Bayer, Berg Health, Biotherapeutics, Blueprint Medicines Corporation, Boston Biomedical, Boston Pharmaceuticals, Celgene, D3, Dragonfly Therapeutics, Exelixis, Fujifilm, GSK, Idera Pharma, Incyte, Inhibrx, Loxo Oncology, Medimmune, MultiVir, Nanocarrier, National Comprehensive Cancer Network, NCI-CTEP, Novartis, Northwest Biotherapeutics, Pfizer, PharmaMar, Roche/Genentech, Takeda, Turning Point Therapeutics, UT MD Anderson Cancer Center, and Vegenics; travel support from ASCO, ESMO, Helsinn, Incyte, Novartis, and PharmaMar; consultancy/advisory board participation for Helsinn, Incyte, Loxo Oncology/Eli Lilly, Medimmune, Novartis, R-Pharma US, QED Pharma, and other relationship with Medscape. V.S. is also an Andrew Sabin Family Foundation Fellow at The University of Texas MD Anderson Cancer Center, acknowledges support of The Jacquelyn A. Brady Fund, is supported by NIH grant R01CA242845. MD Anderson Cancer Center Department of Investigational Cancer Therapeutics is supported by the Cancer Prevention and Research Institute of Texas (RP1100584), the Sheikh Khalifa Bin Zayed Al Nahyan Institute for Personalized Cancer Therapy (1U01 CA180964), NCATS Grant UL1 TR000371 (Center for Clinical and Translational Sciences), and the MD Anderson Cancer Center Support Grant (P30 CA016672).