Tran, Norman
Dasari, Sathish http://orcid.org/0000-0002-5554-9047
Barwell, Sarah A. E.
McLeod, Matthew J. http://orcid.org/0000-0001-5540-916X
Kalyaanamoorthy, Subha
Holyoak, Todd http://orcid.org/0000-0002-7329-1115
Ganesan, Aravindhan http://orcid.org/0000-0001-8689-943X
Funding for this research was provided by:
Gouvernement du Canada | Natural Sciences and Engineering Research Council of Canada
University of Waterloo-Centre for Bioengineering and Biotechnology; University of Waterloo-The Faculty of Science Action Response Fund; Canada First Research Excellence Fund
Article History
Received: 24 August 2022
Accepted: 4 July 2023
First Online: 12 September 2023
Competing interests
: The authors declare the following competing interests: a patent application on the inactive, disulfide-bonded H163A Mpro structure and the discovery that H163 with alanine leading to this unique conformation have been filed in the United States Patent and Trademark Office (serial number: 18/332.095). A.G., T.H., S.K., and N.T. are co-inventors of this patent. The remaining authors declare no competing interests.