Hasan, A. M. Mahedi http://orcid.org/0000-0002-8334-6490
Cremaschi, Paolo http://orcid.org/0000-0001-5349-4188
Wetterskog, Daniel http://orcid.org/0000-0003-4163-6438
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Williams, Scott
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Trigos, Anna http://orcid.org/0000-0002-5915-2952
Trujillo, Blanca http://orcid.org/0000-0002-5541-9699
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Parry, Marina http://orcid.org/0000-0003-3278-9491
Ismail, Mazlina http://orcid.org/0000-0002-1514-3819
Devlies, Wout http://orcid.org/0000-0003-0725-6300
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Naceur-Lombardelli, Cristina http://orcid.org/0000-0002-7097-0307
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Quezada, Sergio
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Parker, Peter
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Hynds, Robert E.
Pearce, David R.
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Moore, David
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Prymas, Paulina
Watkins, Thomas B. K.
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Noorani, Imran
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Barbe, Vittorio
Bola, Supreet Kaur
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Lam, Jie Min
Richard, Corentin
Vendramin, Roberto
Dijkstra, Krijn
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Nicod, Jerome
Dwornik, Angela
Bowles, Kerry
Zaidi, Rija
Gishen, Faye
Stone, Paddy
Stirling, Caroline
Turajlic, Samra
Larkin, James
Pickering, Lisa
Furness, Andrew
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Drake, Will
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Hunter, Nikki
Mangwende, Mary
Pearce, Karla
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Spain, Lavinia
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Lewis, Charlotte
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Messiou, Christina
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Byrne, Fiona
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Lobon, Irene
Coulton, Alexander
Cattin, Anne-Laure
Deng, Daqi
Feng, Hugang
Rowan, Andew
Yousaf, Nadia
Popat, Sanjay
Curtis, Olivia
Milner-Watts, Charlotte
Stamp, Gordon
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Murra, Aida
Korteweg, Justine
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Terry, Lauren
Biano, Jennifer
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Hill, Peter
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Irshad, Sheeba
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Pulman, Georgina
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Phillips-Boyd, Sherene
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Lise, Stefano
Sandhu, Shahneen
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,
Funding for this research was provided by:
Cancer Research UK (A22744)
Article History
Received: 2 June 2022
Accepted: 21 July 2023
First Online: 10 August 2023
Competing interests
: M.J.-H. has received funding from CRUK, NIH National Cancer Institute, IASLC International Lung Cancer Foundation, Lung Cancer Research Foundation, Rosetrees Trust, UKI NETs and NIHR. M.J.-H. has consulted for, and is a member of, the Achilles Therapeutics Scientific Advisory Board and Steering Committee, has received speaker honoraria from Pfizer, Astex Pharmaceuticals, Oslo Cancer Cluster, Bristol Myers Squibb, and is co-inventor on a European patent application relating to methods to detect lung cancer (PCT/US2017/028013). C.S. acknowledges grants from AstraZeneca, Boehringer-Ingelheim, Bristol Myers Squibb, Pfizer, Roche-Ventana, Invitae (previously Archer Dx Inc—collaboration in minimal residual disease sequencing technologies), Ono Pharmaceutical, and Personalis. He is Chief Investigator for the AZ MeRmaiD 1 and 2 clinical trials and is the Steering Committee Chair. He is also Co-Chief Investigator of the NHS Galleri trial funded by GRAIL and a paid member of GRAIL’s Scientific Advisory Board. He receives consultant fees from Achilles Therapeutics (also SAB member), Bicycle Therapeutics (also a SAB member), Genentech, Medicxi, China Innovation Centre of Roche (CICoR) formerly Roche Innovation Centre—Shanghai, Metabomed (until July 2022), and the Sarah Cannon Research Institute C.S has received honoraria from Amgen, AstraZeneca, Bristol Myers Squibb, GlaxoSmithKline, Illumina, MSD, Novartis, Pfizer, and Roche-Ventana. C.S. has previously held stock options in Apogen Biotechnologies and GRAIL, and currently has stock options in Epic Bioscience, Bicycle Therapeutics, and has stock options and is co-founder of Achilles Therapeutics. C.S. also declares a patent application (PCT/US2017/028013) for methods to lung cancer; targeting neoantigens (PCT/EP2016/059401); identifying patent response to immune checkpoint blockade (PCT/EP2016/071471), determining HLA LOH (PCT/GB2018/052004); predicting survival rates of patients with cancer (PCT/GB2020/050221), identifying patients who respond to cancer treatment (PCT/GB2018/051912); methods for lung cancer detection (US20190106751A1). C.S. is an inventor on a European patent application (PCT/GB2017/053289) relating to assay technology to detect tumor recurrence. This patent has been licensed to a commercial entity and under their terms of employment C.S is due a revenue share of any revenue generated from such license(s). M.L. reports grants or contracts from BMS, Shionogi, and AstraZeneca; consulting fees from BioNTech, Bicycle Therapeutics, Janssen, Merck Sorano, Pfizer, and ADC Therapeutics; honoraria from AstraZeneca and Pfizer; and support for attending meetings or travel from MSD, Janssen, and Bayer. S.S. has served on advisory boards for Bristol Myer Squibb, Merck Sharp and Dohme, Astra Zeneca, Janssen and has received institutional grant funding from Merck Sharp and Dohme, Astra Zeneca, Amgen, and Advanced Accelerator Applications (AAA), a Novartis Company, Merck Serono and Roche/Genentech (outside the submitted work). P.C., D.W., and G.A. have a patent on blood methylation markers (GB1915469.9). G.A. received personal fees, grants, and travel support from Janssen and Astellas Pharma; personal fees or travel support from Pfizer, Novartis/AAA, Bayer Healthcare Pharmaceuticals, AstraZeneca, and Sanofi-Aventis; in addition, G.A.’s former employer, The Institute of Cancer Research, receives royalty income from abiraterone and G.A. receives a share of this income through the Institute’s Rewards to Discoverers Scheme. G.A. has received research funding (institutional) from Janssen, Astellas Pharma, and Novartis. All other authors declare no potential conflicts of interest.