Tomita, Akiko http://orcid.org/0000-0002-6810-5365
Sasanuma, Hiroyuki
Owa, Tomoo http://orcid.org/0009-0006-6333-9468
Nakazawa, Yuka http://orcid.org/0000-0002-3835-3093
Shimada, Mayuko
Fukuoka, Takahiro
Ogi, Tomoo http://orcid.org/0000-0002-5492-9072
Nakada, Shinichiro http://orcid.org/0000-0001-9297-1565
Funding for this research was provided by:
Japan Agency for Medical Research and Development (JP17-19ek010929, JP19-23am0401016, JP19-23am0401016, JP19-23am0401016)
MEXT | Japan Society for the Promotion of Science (16K12596, JP19H04269, JP21K18314, 22H03741)
Uehara Memorial Foundation
Takeda Medical Research Foundation
Ichiro Kanehara Foundation for the Promotion of Medical Sciences and Medical Care
Princess Takamatsu Cancer Research Fund
Article History
Received: 31 August 2022
Accepted: 22 August 2023
First Online: 15 September 2023
Competing interests
: S.N. and A.T. contributed to the patent applications as follows: (1) patent applicant: Osaka University, name of inventor(s): Shinichiro NAKADA and Akiko TOMITA, application number: PCT/JP2019/031117 (National Phase entries, Japan), 2020-556604 (Examination, Japan), 201980075266.3 (Examination, China), 19885454.9 (Examination, Europe), and 17/294165 (Examination, US). Specific aspects of the manuscript covered in patent applications: NICER gene editing, SN, and AT. (2) Patent applicant: Osaka University; name of inventor: Shinichiro NAKADA; application number: PCT /JP2022/046917 (Publication, Japan). Specific aspects of the paper covered in the patent application: enhancement of NICER gene editing by gene knockout or knockdown, S.N. T.F. is an employee at Genomedia Inc. The remaining authors declare no competing interests.