Ptashkin, Ryan N.
Ewalt, Mark D. http://orcid.org/0000-0003-4245-752X
Jayakumaran, Gowtham
Kiecka, Iwona
Bowman, Anita S. http://orcid.org/0000-0002-8651-5317
Yao, JinJuan
Casanova, Jacklyn http://orcid.org/0000-0002-3586-7048
Lin, Yun-Te David
Petrova-Drus, Kseniya http://orcid.org/0000-0002-4048-8376
Mohanty, Abhinita S.
Bacares, Ruben
Benhamida, Jamal http://orcid.org/0000-0001-5542-9857
Rana, Satshil
Razumova, Anna
Vanderbilt, Chad http://orcid.org/0000-0002-8114-0237
Balakrishnan Rema, Anoop http://orcid.org/0000-0001-6104-5665
Rijo, Ivelise
Son-Garcia, Julie
de Bruijn, Ino http://orcid.org/0000-0001-5427-4750
Zhu, Menglei
Lachhander, Sean
Wang, Wei
Haque, Mohammad S.
Seshan, Venkatraman E. http://orcid.org/0000-0002-9258-2698
Wang, Jiajing
Liu, Ying
Nafa, Khedoudja
Borsu, Laetitia
Zhang, Yanming
Aypar, Umut
Suehnholz, Sarah P.
Chakravarty, Debyani http://orcid.org/0000-0001-8629-5732
Park, Jae H. http://orcid.org/0000-0002-2903-5130
Abdel-Wahab, Omar http://orcid.org/0000-0002-3907-6171
Mato, Anthony R.
Xiao, Wenbin http://orcid.org/0000-0001-8586-8500
Roshal, Mikhail
Yabe, Mariko
Batlevi, Connie Lee http://orcid.org/0000-0002-9036-9463
Giralt, Sergio
Salles, Gilles http://orcid.org/0000-0002-9541-8666
Rampal, Raajit http://orcid.org/0000-0002-0355-6368
Tallman, Martin
Stein, Eytan M.
Younes, Anas http://orcid.org/0000-0002-0001-4133
Levine, Ross L. http://orcid.org/0000-0002-7884-1905
Perales, Miguel-Angel http://orcid.org/0000-0002-5910-4571
van den Brink, Marcel R. M. http://orcid.org/0000-0003-0696-4401
Dogan, Ahmet http://orcid.org/0000-0001-6576-5256
Ladanyi, Marc
Berger, Michael F. http://orcid.org/0000-0003-3882-5000
Brannon, A. Rose http://orcid.org/0000-0003-4610-0149
Benayed, Ryma
Zehir, Ahmet http://orcid.org/0000-0001-5406-4104
Arcila, Maria E. http://orcid.org/0000-0001-5824-6554
Funding for this research was provided by:
U.S. Department of Health & Human Services | NIH | National Cancer Institute (P30 CA008748)
Article History
Received: 5 April 2023
Accepted: 16 October 2023
First Online: 28 October 2023
Competing interests
: The authors declare the following competing interests: Ryan N. Ptashkin is an employee of C2i Genomics. Gowtham Jayakumaran is an employee of Guardant Health. Chad Vanderbilt reports intellectual property rights and equity interest in Paige.AI, Inc. Menglei Zhu has received advisory or consulting fees from Leica Biosystems. Jae Park has received advisory or consulting fees from Allogene, Amgen, Artiva, Autolus, BMS, Curocel, Incyte, InnatePharma, Kite Pharma, Kura Oncology, Minerva, Novartis, Pfizer, PrecisionBio, Servier, and served on a data monitoring committee for Affyimmune, BrightPharma and Intellia. Omar Abdel-Wahab has served as a consultant for H3B Biomedicine, Foundation Medicine Inc, Merck, and Janssen; is on the Scientific Advisory Board of Pfizer Boulder, Envisagenics Inc., and AIChemy; and has received prior research funding from H3B Biomedicine, Loxo/Lilly, and Nurix Therapeutics. Anthony Mato has received research funding from TG Therapeutics, Pharmacyclics, AbbVie, Johnson and Johnson, Astra Zeneca, DTRM BioPharma, BeiGene, Genentech, Genmab Janssen, LOXO, Nurix, Octopharma, Pfizer and has received honoraria from TG Therapeutics, Pharmacyclics LLC, AbbVie, Adaptive Biotechnologies, Johnson and Johnson AcertaDTRM BioPharma, Nurix, AstraZeneca BeiGene Genentech Janssen LOXO, Curio, Dava, Octopharma, Genmab, BMS, Medscape, PER, PerView. Mikhail Roshal has received research funding from Roche, NGM, and Beat AML and has served on an advisory board and holds stock/stock options in Auron Therapeutics. Mariko Yabe has served as a consultant for Janssen R&D. Connie Batlevi has received advisory or consulting fees from ADC Therapeutics, AbbVie, Bristol-Myers Squibb, Dava Oncology, Defined Health, Epizyme, Gerson Lehrman Group, Juno Therapeutics, Karyopharm, Kite Pharmaceuticals, LifeSci Capital, LLC, Medscape, MorphoSys AG, NeuroAxis LLC, Seattle Genetics, Skipta LLC, TG Therapeutics, Inc, Touch Independent Medical Education Ltd, and Treeline Biosciences, Inc., and reports ownership/equity interest in Bristol-Myers Squibb, Moderna, Inc., Novavax, Pfizer, Inc., Regeneron Pharmaceuticals, Inc., and Viatris Inc. Sergio Giralt has received advisory or consulting fees from Amgen, CSL Behring, Caladrius, Celgene, Ceramedix, ExpertConnect, GlaxoSmithKline, Janssen Research & Development, LLC, Karyopharm, Kite Pharmaceuticals, Magnolia Innovation, Novartis, Omeros, Pfizer, Inc., Physicians’ Education Resource, Sanofi US Services Inc., TRM Oncology, and Xcenda. Gilles Salles has received advisory or consulting fees from Abbvie, Beigene, Bayer, BMS/Celgene, Epizyme, Genentech/Roche, Genmab, Incyte, Ipsen, Janssen, Kite/Gilead, Loxo, Milteniy, Molecular Partners, Morphosys, Nordic Nanovector, Novartis, Rapt, Regeneron, and Takeda, and reports equity interest in Owkin. Raajit Rampal has received advisory or consulting fees from Constellation, Incyte, Celgene/BMS, Novartis, Promedior, CTI, Jazz Pharmaceuticals, Blueprint, Stemline, Galecto, PharmaEssentia, AbbVie, Sierra Oncology,Servier, and Disc Medicines; and research funding from Incyte, Constellation, and Stemline. Eytan Stein has received advisory or consulting fees from AbbVie, Agios Pharmaceuticals, Bristol-Myers Squibb, CTI BioPharma Corp., Calithera, Celgene, Epizyme, Genentech, Genesis Therapeutics, Gilead Pharmaceutical, Janssen Pharmaceuticals, Inc., Jazz Pharmaceuticals, Kronos Bio, Inc, Kura Oncology, Neoleukin Therapeutics, Inc., Novartis Pharmaceuticals Corporation, PinotBio, Inc., Servier, Syndax, and Takeda Millennium, and reports ownership/equity interests in Auron Therapeutics, Inc. Anas Younes is an employee of AstraZeneca. Ross Levine is on the supervisory board of Qiagen and is a scientific advisor to Imago, Mission Bio, Syndax. Zentalis, Ajax, Bakx, Auron, Prelude, C4 Therapeutics and Isoplexis for which he receives equity support; receives research support from Ajax and Abbvie; has consulted for Incyte, Janssen, Morphosys and Novartis; and has received honoraria from Astra Zeneca and Kura for invited lectures. Miguel Perales reports honoraria from Abbvie, Allovir, Astellas, Bristol-Myers Squibb, Caribou Biosciences, Celgene, Equilium, Exevir, Incyte, Karyopharm, Kite/Gilead, Merck, Miltenyi Biotec, MorphoSys, Novartis, Nektar Therapeutics, Omeros, OrcaBio, Takeda, and VectivBio AG, Vor Biopharma; serves on DSMBs for Cidara Therapeutics, Medigene, Sellas Life Sciences, and Servier, and the scientific advisory board of NexImmune; has ownership interests in NexImmune and Omeros; and has received institutional research support for clinical trials from Incyte, Kite/Gilead, Miltenyi Biotec, Nektar Therapeutics, and Novartis. Marcel van den Brink has received advisory or consulting fees from Ceramedix, DKMS, Da Volterra, Garuda Therapeutics, GlaxoSmithKline, LyGenesis, Inc., Vor Biopharma, Pluto Immunotherapeutics, Rheos Medicines, Inc, Seres Therapeutics, Frazier Healthcare Partners, and Notch Therapeutics and has ownership/equity interests in Pluto Immunotherapeutics, Seres Therapeutics, ThymoFox, Inc., and Notch Therapeutics and is in a fiduciary role/position for DKMS, holds intellectual property rights with Juno Therapeutics and Seres Therapeutics, and has received royalties from Wolters Kluwer. Ahmet Dogan has received advisory or consulting fees from Incyte, Loxo Oncology, and Physicians’ Education Resource and has received research funding from Roche and Takeda. Marc Ladanyi has received advisory or consulting fees from Takeda Oncology, Janssen Pharmaceuticals, AstraZeneca, ADC Therapeutics, Paige.AI, Merck, Bayer, and Lilly Oncology and has received research funding from Loxo Oncology, Helsinn Therapeutics, Merus NV, Elevation Oncology, and Rain Therapeutics. Michael Berger has received advisory or consulting fees from AstraZeneca, Eli Lilly and Company, and PetDx, Inc. A. Rose Brannon has ownership/equity interests in Johnson and Johnson. Ryma Benayed is an employee of AstraZeneca. Ahmet Zehir is an employee of AstraZeneca. Maria Arcila has received advisory or consulting fees from Axis Medical Education, Clinical Education Alliance, LLC, Merck Sharp & Dohme, PeerView Institute for Medical Education (PVI), Physicians’ Education Resource, RMEI Medical Education, LLC, and Roche. The following Authors declare no competing interests: Mark D. Ewalt, Iwona Kiecka, Anita S. Bowman, JinJuan Yao, Jacklyn Casanova, Yun-Te David Lin, Kseniya Petrova-Drus, Abhinita S. Mohanty, Ruben Bacares, Jamal Benhamida, Satshil Rana, Anna Razumova, Anoop Balakrishnan Rema, Ivelise Rijo, Julie Son-Garcia, Ino de Bruijn, Sean Lachhander, Wei Wang, Mohammad S. Haque, Venkatraman E. Seshan, Jiajing Wang, Ying Liu, Khedoudja Nafa, Laetitia Borsu, Yanming Zhang, Umut Aypar, Sarah P. Suehnholz, Debyani Chakravarty, Wenbin Xiao, and Martin Tallman.