Anderson, Aidan
Alfahad, Nada
Wimalachandra, Dulani
Bouzinab, Kaouthar
Rudzinska, Paula
Wood, Heather
Fazey, Isabel
Xu, Heping http://orcid.org/0000-0003-4000-931X
Lyons, Timothy J. http://orcid.org/0000-0003-2106-1622
Barnes, Nicholas M.
Narendran, Parth
Lord, Janet M. http://orcid.org/0000-0003-1030-6786
Rauz, Saaeha http://orcid.org/0000-0003-4627-3496
Ganley, Ian G. http://orcid.org/0000-0003-1481-9407
Curtis, Tim M.
Wallace, Graham R.
Hombrebueno, Jose R. http://orcid.org/0000-0003-1094-2977
Funding for this research was provided by:
Diabetes UK (20/0006296)
Fight for Sight UK (1842/1843)
European Foundation for the Study of Diabetes (EFSD/Boehringer Ingelheim grant)
Wellcome Trust (213458/Z/18/Z)
RCUK | Medical Research Council (MC_UU_00018/2)
Article History
Received: 18 July 2023
Accepted: 23 January 2024
First Online: 6 February 2024
Competing interests
: The authors declare no competing interests.
: Human studies were approved by the Oklahoma Health Sciences Centre (OUHSC) and conducted according to the Declaration of Helsinki principles. Written informed consent was received from participants prior to inclusion in the study. Animal studies were approved by the Ethics Committee of the University of Birmingham (Project Licence Number PP6860623) and Queen’s University Belfast (Project Licence Number PPL2814). All animal procedures were approved by the Ethical Review Body (AWERB) and authorized under the UK Animals (Scientific Procedures) Act 1986. Animal use conformed to the standards in the Association for Research in Vision and Ophthalmology (ARVO) Statement for the Use of Animals in Ophthalmic and Vision Research and with European Directive 210/63/EU.