Morinan, Gareth http://orcid.org/0000-0001-9727-5630
Dushin, Yuriy http://orcid.org/0000-0002-6060-299X
Sarapata, Grzegorz http://orcid.org/0000-0001-9021-6232
Rupprechter, Samuel
Peng, Yuwei
Girges, Christine
Salazar, Maricel
Milabo, Catherine
Sibley, Krista
Foltynie, Thomas http://orcid.org/0000-0003-0752-1813
Cociasu, Ioana http://orcid.org/0000-0003-0232-6509
Ricciardi, Lucia
Baig, Fahd http://orcid.org/0000-0002-3315-2698
Morgante, Francesca
Leyland, Louise-Ann
Weil, Rimona S. http://orcid.org/0000-0002-5092-6325
Gilron, Ro’ee
O’Keeffe, Jonathan
Funding for this research was provided by:
Innovate UK
Machine Medicine Technologies, Capital Enterprise
Article History
Received: 9 August 2022
Accepted: 13 January 2023
First Online: 27 January 2023
Ethics statement
: Ethical approval for the capture of the Kelvin data was obtained from the National Hospital for Neurology and Neurosurgery Research Ethics Committee (19/YH/0421). Written informed consent was obtained from all subjects and agreements were formed with institutions providing the data to be used in this research. Data was collected at: Department of Clinical and Movement Neurosciences, Institute of Neurology, University College London; Neuroscience Research Centre, Molecular and Clinical Sciences Research Institute, St. George’s, University of London; Dementia Research Center, Institute of Neurology, University College London; Parkinson’s Disease and Movement Disorders Center, Baylor College of Medicine; The Starr Lab, University of California San Francisco. Data were collected according to the approval and ethics procedures of each participating institution. A subset of the data has been collected as part of clinical trials: Trial of Exenatide for Parkinson’s Disease (EXENATIDE-PD, NCT01971242), Antidepressants Trial in Parkinson’s Disease (ADepT-PD, NCT03652870) and The Motor Network in Parkinson’s Disease and Dystonia: Mechanisms of Therapy (NCT03582891). Explicit written consent was obtained for publishing all patient photographs presented in this research.
: Gareth Morinan, Yuriy Dushin, Grzegorz Sarapata, Samuel Rupprechter, Yuwei Peng, and Jonathan O’Keeffe declare no Competing Non-Financial Interests but the following Competing Financial Interests: this work was performed during their employment at Machine Medicine Technologies, owner of the Kelvin platform used in this research. Francesca Morgante declares no Competing Non-Financial Interests and the following Competing Financial Interests: speaking honoraria from Abbvie, Medtronic, Zambon, Bial, Merz; Travel grants from the International Parkinson’s disease and Movement Disorder Society; Advisory board fees from Merz; Consultancy fees from Merz and Bial; Research support from Boston Scientific, Merz and Global Kinetics; Royalties from Springer; member of the editorial board of Movement Disorders, Movement Disorders Clinical Practice, European Journal of Neurology. Ramona Weil declares no Competing Non-Financial Interests and the following Competing Financial Interests: speaking honoraria from GE Healthcare and a writing honorarium from Britannia. Thomas Foltynie declares no Competing Non-Financial Interests and the following Competing Financial Interests: the work conducted for this project was funded by Innovate UK. Christine Girges, Krista Sibley, Fahd Baig, Ro’ee Gilron, Catherine Milabo, Maricel Salazar, Ioana Cociasu, Lucia Ricciardi, Louise-Ann Leyland declare no competing interests.