W. H. Kocks, Janwillem http://orcid.org/0000-0002-2760-0693
Wouters, Hans
Bosnic-Anticevich, Sinthia http://orcid.org/0000-0001-5077-8329
van Cooten, Joyce
Correia de Sousa, Jaime http://orcid.org/0000-0001-6459-7908
Cvetkovski, Biljana http://orcid.org/0000-0003-2297-8141
Dekhuijzen, Richard
Dijk, Lars http://orcid.org/0000-0002-9544-1487
Dvortsin, Evgeni
Garcia Pardo, Marina http://orcid.org/0000-0002-4183-8219
Gardev, Asparuh
Gawlik, Radosław
van Geer - Postmus, Iris
van der Ham, Iris http://orcid.org/0000-0003-1054-3415
Harbers, Marten
de la Hoz, Alberto
Janse, Ymke
Kerkhof, Marjan
Lavorini, Federico http://orcid.org/0000-0002-3293-2123
Maricoto, Tiago http://orcid.org/0000-0002-4201-9565
Meijer, Jiska
Metz, Boyd http://orcid.org/0000-0002-7949-2559
Price, David http://orcid.org/0000-0002-9728-9992
Roman-Rodriguez, Miguel
Schuttel, Kirsten http://orcid.org/0000-0001-7346-6360
Stoker, Nilouq http://orcid.org/0000-0002-0023-6529
Tsiligianni, Ioanna
Usmani, Omar
Leving, Marika T. http://orcid.org/0000-0002-2732-4406
Funding for this research was provided by:
Boehringer Ingelheim
Article History
Received: 19 October 2021
Accepted: 10 May 2022
First Online: 26 May 2022
Competing interests
: J.K. reports grants, personal fees and non-financial support from AstraZeneca, GSK and Boehringer Ingelheim; grants and personal fees from Chiesi Pharmaceuticals and TEVA; grants from Mundipharma; personal fees from MSD and COVIS Pharma; and also holds 72.5% of shares in the General Practitioners Research Institute. H.W. has received grants from Boehringer Ingelheim, which is the financial and scientific partner of GPRI for the submitted study, and from AstraZeneca, Novartis and Chiesi for scientific projects in the area of COPD/asthma. S.B.-A. has received grants from TEVA, and personal fees from TEVA, Boehringer Ingelheim, AstraZeneca, GSK, Sanofi and Mylan. J.C.d.S. reports or personal fees from AstraZeneca, Bial, Boehringer Ingelheim, GSK, Medinfar, Mundipharma and Sanofi. B.C. received honorarium from GSK and Sanofi. J.v.C., L.D., I.v.G.-P., I.v.d.H., Y.J., M.K., B.M., K.S., N.S., M.H., B.M. and M.T.L. were employed by General Practitioners Research Institute (GPRI) at the time of the study. In the past three years (2019–2021), GPRI conducted investigator- and sponsor-initiated research funded by non-commercial organizations, academic institutes, and pharmaceutical companies (including AstraZeneca, Boehringer Ingelheim, Chiesi, GSK, Mundipharma, Novartis, and Teva). R.D. has received grants and personal fees from TEVA, Boehringer Ingelheim, AstraZeneca, GSK, Chiesi, Focus Care, and Glenmark. R.G. has received personal fees from AstraZeneca, GSK and Chiesi. E.D. holds 27.5% of shares in the General Practitioners Research Institute. M.G.P. receives grants from AstraZeneca, GSK and Boehringer Ingelheim. A.G. and A.d.l.H. are employees of Boehringer Ingelheim. F.L. received grants and personal fees from GSK, personal fees from AstraZeneca, Boehringer Ingelheim, Chiesi, Menarini International, Novartis, Orion, and Trudell International, outside the submitted work. T.M. is an Assoicate Editor at <i>npj Primary Care Respiratory Medicine</i>. J.M. received grants from Boehringer Ingelheim, during the conduct of the study; and grants from AstraZeneca, Chiesi, Novartis, and GSK, outside the submitted work. D.P. reports grants and personal fees from AstraZeneca, Boehringer Ingelheim, Chiesi, Mylan, Novartis, Regeneron Pharmaceuticals, Sanofi Genzyme, Theravance and Zentiva (Sanofi Generics); grants from the British Lung Foundation, Respiratory Effectiveness Group, UK National Health Service, and AKL Research and Development Ltd; personal fees from Cipla, GlaxoSmithKline, Kyorin, Merck, Mundipharma, Airway Vista Secretariat, EPG Communication Holdings Ltd, FIECON Ltd, Fieldwork International, OM Pharma SA, PeerVoice, Phadia AB, Spirosure Inc, Strategic North Limited, Synapse Research Management Partners S.L., Talos Health Solutions, and WebMD Global LLC; non-financial support from Efficacy and Mechanism Evaluation programme and Health Technology Assessment; stock/stock options from AKL Research and Development Ltd, which produces phytopharmaceuticals; owns 74% of the social enterprise Optimum Patient Care Ltd (Australia and UK) and 92.61% of Observational and Pragmatic Research Institute Pte Ltd (Singapore); and 5% shareholding in Timestamp, which develops adherence monitoring technology. M.R.-R. receives grants and personal fees from AstraZeneca and GSK; and personal fees from Boehringer Ingelheim, Chiesi, Menarini, Mundipharma, Novartis, Pfizer, TEVA and BIAL. I.T. reports grants and personal fees from GSK, AstraZeneca, Boehringer Ingelheim, Menarini, Novartis, Chiesi and Elpen. O.U. reports grants and personal fees from AstraZeneca, Boehringer Ingelheim, Edmond Pharma, Chiesi and GSK; grants from Edmond Pharma; and personal fees from Napp, Mundipharma, Sandoz, Takeda, Cipla, COVIS, Novartis, Mereobiopharma, Orion, and Menarini. S.B.-A. and T.M. are Associate Editors at <i>npj Primary Care Respiratory Medicine</i>, and I.T. is Editor in Chief. These authors were not involved in the journal’s review of, or decisions related to, this manuscript.