Liu, Zhen http://orcid.org/0000-0002-1119-0693
Calvó-Tusell, Carla http://orcid.org/0000-0003-2681-8460
Zhou, Andrew Z. http://orcid.org/0000-0002-1763-7353
Chen, Kai http://orcid.org/0000-0002-3325-3536
Garcia-Borràs, Marc http://orcid.org/0000-0001-9458-1114
Arnold, Frances H. http://orcid.org/0000-0002-4027-364X
Article History
Received: 14 April 2021
Accepted: 23 August 2021
First Online: 18 October 2021
Competing interests
: K.C., Z.L. and A.Z.Z. are inventors on a US Patent Application (invention title, Diverse Carbene Transferase Enzyme Catalysts Derived from a P450 Enzyme; application no., 17/200,394) filed by the California Institute of Technology, which covers lactone-carbene N–H insertion with engineered P450 enzymes. The patent was filed on 12 March 2021. The remaining authors declare no competing interests.