Masoodi, Mojgan http://orcid.org/0000-0001-9840-1731
Gastaldelli, Amalia http://orcid.org/0000-0003-2594-1651
Hyötyläinen, Tuulia
Arretxe, Enara
Alonso, Cristina http://orcid.org/0000-0002-2019-678X
Gaggini, Melania
Brosnan, Julia
Anstee, Quentin M. http://orcid.org/0000-0002-9518-0088
Millet, Oscar
Ortiz, Pablo http://orcid.org/0000-0002-2698-8470
Mato, Jose M. http://orcid.org/0000-0003-1264-3153
Dufour, Jean-Francois http://orcid.org/0000-0002-8062-1346
Orešič, Matej
Article History
Accepted: 15 July 2021
First Online: 10 September 2021
Competing interests
: J.B. was an employee and shareholder of Pfizer. E.A., C.A. and P.O. are employees of OWL Metabolomics. A.G. is a consultant for Eli Lilly, Inventiva, Genentech, Menarini, Gilead, Novo Nordisk, AstraZeneca and Boehringer outside the submitted work. J.-F.D. is on advisory committees for Abbvie, Bayer, BMS, Falk, Genfit, Genkyotex, Gilead Science, HepaRegenix, Intercept, Lilly, Merck and Novartis; speaking and teaching at Bayer, BMS, Intercept, Genfit, Gilead Science and Novartis. Q.M.A. has active research collaborations (including research collaborations supported through the EU IMI2 LITMUS Consortium*) with Abbvie, Antaros Medical*, Allergan/Tobira*, AstraZeneca*, BMS*, Boehringer Ingelheim International GMBH*, Echosens*, Ellegaard Gottingen Minipigs AS*, Eli Lilly & Company Ltd.*, Exalenz Bioscience Ltd.*, Genfit SA*, Glympse Bio, GlaxoSmithKline, HistoIndex*, Intercept Pharma Europe Ltd.*, iXscient Ltd.*, Nordic Bioscience*, Novartis Pharma AG*, Novo Nordisk A/S*, One Way Liver SL*, Perspectum Diagnostics*, Pfizer Ltd.*, Resoundant*, Sanofi-Aventis Deutschland GMBH*, SomaLogic Inc.* and Takeda Pharmaceuticals International SA*, acts as a consultant for 89Bio, Abbott Laboratories, Acuitas Medical, Allergan/Tobira, Altimmune, AstraZeneca, Axcella, Blade, BMS, BNN Cardio, Celgene, Cirius, CymaBay, EcoR1, E3Bio, Eli Lilly & Company Ltd., Galmed, Genentech, Genfit SA, Gilead, Grunthal, HistoIndex, Indalo, Imperial Innovations, Intercept Pharma Europe Ltd., Inventiva, IQVIA, Janssen, Madrigal, MedImmune, Metacrine, NewGene, NGMBio, North Sea Therapeutics, Novartis, Novo Nordisk A/S, Pfizer Ltd., Poxel, ProSciento, Raptor Pharma, Servier, Terns, Viking Therapeutics and Speaker for Abbott Laboratories, Allergan/Tobira, BMS, Clinical Care Options, Falk, Fishawack, Genfit SA, Gilead, Integritas Communications, Kenes and MedScape, and has received royalties from Elsevier Ltd (Davidson’s Principles & Practice of Medicine textbook). All other authors declare no competing interests.