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Article History
Accepted: 14 January 2020
First Online: 24 February 2020
Competing interests
: The authors declare support from academic grants but have no other competing interests. The authors’ institutions receive grant support related to the work described in the paper from the Fondation Leducq (16 CVD 05), the USA National Institutes of Health, the UK Medical Research Council, Stroke Association, Alzheimer’s Society, and Row Fogo Charitable Trust.