Chan, Edmond M.
Shibue, Tsukasa
McFarland, James M.
Gaeta, Benjamin
Ghandi, Mahmoud
Dumont, Nancy
Gonzalez, Alfredo
McPartlan, Justine S.
Li, Tianxia
Zhang, Yanxi
Bin Liu, Jie
Lazaro, Jean-Bernard
Gu, Peili
Piett, Cortt G.
Apffel, Annie
Ali, Syed O.
Deasy, Rebecca
Keskula, Paula
Ng, Raymond W. S.
Roberts, Emma A.
Reznichenko, Elizaveta
Leung, Lisa
Alimova, Maria
Schenone, Monica
Islam, Mirazul
Maruvka, Yosef E.
Liu, Yang
Roper, Jatin
Raghavan, Srivatsan
Giannakis, Marios
Tseng, Yuen-Yi
Nagel, Zachary D.
D’Andrea, Alan
Root, David E.
Boehm, Jesse S.
Getz, Gad
Chang, Sandy
Golub, Todd R.
Tsherniak, Aviad
Vazquez, Francisca
Bass, Adam J.
Article History
Received: 7 August 2018
Accepted: 27 February 2019
First Online: 10 April 2019
Competing interests
: A.J.B. receives research funding from Merck and Novartis. D.E.R. receives research funding from the Functional Genomics Consortium (Abbvie, Jannsen, Merck and Vir) and is a director of Addgene. A.T. consults for Tango Therapeutics. T.R.G. has advised Foundation Medicine, GlaxoSmithKline, Sherlock Biosciences and Forma Therapeutics. A.D.A. consults for Lilly Oncology, EMD Serono, Intellia Therapeutics, Sierra Oncology, Formation Biologics and Cyteir Therapeutics, consults and holds stock in Ideaya, and co-founded and holds stock in Cedilla Therapeutics. G.G. receives research funding from IBM and Pharmacyclics and is an inventor on multiple patent applications related to bioinformatics tools, including applications related to MuTect, ABSOLUTE, MSMuTect, MSMutSig and MSIClass. Y.E.M. is an inventor on patent applications related to the bioinformatics tools MSMuTect, MSMutSig and MSIClass. The Broad Institute, on behalf of E.M.C., T.S., J.M.M., M. Ghandi, F.V. and A.J.B., filed a US patent application related to the target described in this manuscript.