Da Mesquita, Sandro http://orcid.org/0000-0002-0786-5010
Papadopoulos, Zachary
Dykstra, Taitea http://orcid.org/0000-0001-7756-809X
Brase, Logan http://orcid.org/0000-0002-7175-3208
Farias, Fabiana Geraldo http://orcid.org/0000-0002-5215-7304
Wall, Morgan
Jiang, Hong
Kodira, Chinnappa Dilip
de Lima, Kalil Alves http://orcid.org/0000-0002-9149-168X
Herz, Jasmin http://orcid.org/0000-0001-6325-863X
Louveau, Antoine
Goldman, Dylan H.
Salvador, Andrea Francesca http://orcid.org/0000-0002-9197-7575
Onengut-Gumuscu, Suna
Farber, Emily
Dabhi, Nisha
Kennedy, Tatiana
Milam, Mary Grace
Baker, Wendy
Smirnov, Igor
Rich, Stephen S. http://orcid.org/0000-0003-3872-7793
Benitez, Bruno A. http://orcid.org/0000-0002-2699-3878
Karch, Celeste M. http://orcid.org/0000-0002-6854-5547
Perrin, Richard J. http://orcid.org/0000-0002-3443-7716
Farlow, Martin
Chhatwal, Jasmeer P.
Holtzman, David M.
Cruchaga, Carlos
Harari, Oscar http://orcid.org/0000-0002-2635-6975
Kipnis, Jonathan http://orcid.org/0000-0002-3714-517X
,
Article History
Received: 27 January 2020
Accepted: 25 March 2021
First Online: 28 April 2021
Competing interests
: J.K. is a member of a scientific advisory group for PureTech. J.K., S.D.M. and A.L. hold patents and patent applications related to the findings described herein. D.M.H. is an inventor on a patent for anti-Aβ antibodies licensed to Eli Lilly by Washington University. D.M.H. and H.J. are inventors on a patent for anti-apoE antibodies licensed to NextCure. D.M.H. and H.J. are listed as inventors on a patent licensed by Washington University to C2N Diagnostics on the therapeutic use of anti-tau antibodies. D.M.H. co-founded and is on the scientific advisory board of C2N Diagnostics. C2N Diagnostics has licensed certain anti-tau antibodies to AbbVie for therapeutic development. D.M.H. is on the scientific advisory board of Denali and consults for Genentech, Merck, and Cajal Neuroscience. C.C. receives research support from Biogen, EISAI, Alector and Parabon. The funders of the study had no role in the collection, analysis, or interpretation of data, in the writing of the manuscript, or in the decision to submit the paper for publication. C.C. is a member of the advisory board of Vivid Genetics, Halia Therapeutics and ADx Healthcare. J.P.C. has served on a medical advisory board for Otsuka Pharmaceuticals. The authors declare no other competing interests.