Schiepers, Ariën http://orcid.org/0000-0002-5185-364X
van ’t Wout, Marije F. L.
Greaney, Allison J.
Zang, Trinity
Muramatsu, Hiromi http://orcid.org/0000-0003-1544-1493
Lin, Paulo J. C.
Tam, Ying K. http://orcid.org/0000-0002-4083-5251
Mesin, Luka
Starr, Tyler N.
Bieniasz, Paul D. http://orcid.org/0000-0002-2368-3719
Pardi, Norbert http://orcid.org/0000-0003-1008-6242
Bloom, Jesse D. http://orcid.org/0000-0003-1267-3408
Victora, Gabriel D. http://orcid.org/0000-0001-8807-348X
Article History
Received: 29 August 2022
Accepted: 6 January 2023
First Online: 16 January 2023
Competing interests
: N.P. is named on a patent (62/153,143 — Nucleoside-modified RNA inducing an adaptive immune response), describing the use of nucleoside-modified mRNA in LNPs as a vaccine platform. He has disclosed those interests fully to the University of Pennsylvania and has an approved plan in place for managing any potential conflicts arising from the licensing of that patent. P.J.C.L. and Y.K.T. are employees of Acuitas Therapeutics, a company that is involved in the development of mRNA–LNP therapeutics. Y.K.T. is named on a patent (WO 2017/004143 — Lipids and lipid nanoparticle formulations for delivery of nucleic acids) that describes LNPs for the delivery of nucleic acid therapeutics, including mRNA, and the use of modified mRNA in lipid nanoparticles as a vaccine platform. P.D.B. has done consulting work in the area of COVID vaccines for Pfizer. J.D.B. consults or has recently consulted for Apriori Bio, Oncorus, Merck and Moderna on topics related to viruses, vaccines and viral evolution. J.D.B, T.N.S. and A.J.G. are listed as inventors on Fred Hutch licensed patents (62/935,954 and 62/692,398) related to viral deep mutational scanning. G.D.V. and J.D.B. are advisors for the Vaccine Company.
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