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Article History
Received: 25 March 2022
Accepted: 21 December 2023
First Online: 14 February 2024
Competing interests
: A patent on the repurposing of SIRT1 inhibitors has been filed by the University of Cambridge. The data presented in this patent are included in the main paper and InternalRef removed. D.J.A. is a consultant for Microbiotica and Ono Therapeutics and receives research funding from Astra Zeneca and OpenTargets. M.R. is employed by Artios Pharma and is also a shareholder. J.R.B.P. is an employee of Insmed Innovation UK and holds stock/stock options in Insmed, and also receives research funding from GSK. The other authors declare no competing interests.