Nagata, Tetsuya
Dwyer, Chrissa A.
Yoshida-Tanaka, Kie
Ihara, Kensuke
Ohyagi, Masaki http://orcid.org/0000-0002-6009-450X
Kaburagi, Hidetoshi
Miyata, Haruka
Ebihara, Satoe
Yoshioka, Kotaro http://orcid.org/0000-0001-7094-9017
Ishii, Takashi
Miyata, Kanjiro http://orcid.org/0000-0001-7044-190X
Miyata, Kenichi
Powers, Berit
Igari, Tomoko
Yamamoto, Syunsuke
Arimura, Naoto
Hirabayashi, Hideki
Uchihara, Toshiki
Hara, Rintaro Iwata http://orcid.org/0000-0003-2399-3431
Wada, Takeshi
Bennett, C. Frank http://orcid.org/0000-0001-9887-6251
Seth, Punit P.
Rigo, Frank
Yokota, Takanori http://orcid.org/0000-0002-6490-3263
Funding for this research was provided by:
Japan Agency for Medical Research and Development (20am0401006h0002, 19ek0610013h0003, 19ek0610013h0003)
MEXT | Japan Society for the Promotion of Science (17H06109, 19H01016, 17H06109, 19H01016)
MEXT | Japan Science and Technology Agency (JPMJCR12L4)
Article History
Received: 22 September 2020
Accepted: 2 June 2021
First Online: 12 August 2021
Competing interests
: T.Y. is collaborating with Daiichi Sankyo Co., Ltd. (Tokyo, Japan), Mitsubishi Tanabe Pharma Corporation (Osaka, Japan), NanoCarrier Co., Ltd. (Chiba, Japan), Ono Pharmaceutical Co., Ltd. (Osaka, Japan), Rena Therapeutics Inc. (Tokyo, Japan), Takeda Pharmaceutical Co., Ltd. (Tokyo, Japan) and Toray Industries, Inc. (Tokyo, Japan) and Ionis Pharmaceuticals (CA, USA). T.Y. also serves as academic adviser for Rena Therapeutics Inc. C.A.D., B.P., C.F.B., P.P.S. and F.R. are paid employees of Ionis Pharmaceuticals, Inc. Kenichi Miyata, T. Igari, S.Y., N.A. and H.H. are paid employees of Takeda Pharmaceutical Company Limited. T.Y. and T.N. are inventors on patents on BBB-HDO filed by Tokyo Medical and Dental University and have benefits from licensing of the associated intellectual property.