Tin, Adrienne http://orcid.org/0000-0002-4207-5866
,
Marten, Jonathan http://orcid.org/0000-0001-6916-2014
Halperin Kuhns, Victoria L.
Li, Yong http://orcid.org/0000-0003-2651-8791
Wuttke, Matthias http://orcid.org/0000-0003-3420-5082
Kirsten, Holger http://orcid.org/0000-0002-3126-7950
Sieber, Karsten B.
Qiu, Chengxiang http://orcid.org/0000-0002-6346-8669
Gorski, Mathias
Yu, Zhi
Giri, Ayush http://orcid.org/0000-0002-7786-4670
Sveinbjornsson, Gardar
Li, Man http://orcid.org/0000-0002-3839-0281
Chu, Audrey Y.
Hoppmann, Anselm
O’Connor, Luke J. http://orcid.org/0000-0003-2730-9668
Prins, Bram
Nutile, Teresa
Noce, Damia
Akiyama, Masato
Cocca, Massimiliano
Ghasemi, Sahar
van der Most, Peter J. http://orcid.org/0000-0001-8450-3518
Horn, Katrin http://orcid.org/0000-0002-5307-6936
Xu, Yizhe
Fuchsberger, Christian
Sedaghat, Sanaz
Afaq, Saima
Amin, Najaf
Ärnlöv, Johan
Bakker, Stephan J. L.
Bansal, Nisha
Baptista, Daniela
Bergmann, Sven http://orcid.org/0000-0002-6785-9034
Biggs, Mary L.
Biino, Ginevra http://orcid.org/0000-0002-9936-946X
Boerwinkle, Eric
Bottinger, Erwin P.
Boutin, Thibaud S.
Brumat, Marco http://orcid.org/0000-0003-3268-039X
Burkhardt, Ralph
Campana, Eric
Campbell, Archie http://orcid.org/0000-0003-0198-5078
Campbell, Harry
Carroll, Robert J.
Catamo, Eulalia
Chambers, John C.
Ciullo, Marina
Concas, Maria Pina http://orcid.org/0000-0003-3598-2537
Coresh, Josef http://orcid.org/0000-0002-4598-0669
Corre, Tanguy
Cusi, Daniele
Felicita, Sala Cinzia http://orcid.org/0000-0003-2514-2075
de Borst, Martin H. http://orcid.org/0000-0002-4127-8733
De Grandi, Alessandro
de Mutsert, Renée
de Vries, Aiko P. J.
Delgado, Graciela
Demirkan, Ayşe
Devuyst, Olivier http://orcid.org/0000-0003-3744-4767
Dittrich, Katalin
Eckardt, Kai-Uwe
Ehret, Georg http://orcid.org/0000-0002-5730-0675
Endlich, Karlhans http://orcid.org/0000-0001-6052-6061
Evans, Michele K.
Gansevoort, Ron T.
Gasparini, Paolo
Giedraitis, Vilmantas http://orcid.org/0000-0003-3423-2021
Gieger, Christian
Girotto, Giorgia http://orcid.org/0000-0003-4507-6589
Gögele, Martin
Gordon, Scott D. http://orcid.org/0000-0001-7623-328X
Gudbjartsson, Daniel F. http://orcid.org/0000-0002-5222-9857
Gudnason, Vilmundur http://orcid.org/0000-0001-5696-0084
Haller, Toomas
Hamet, Pavel
Harris, Tamara B.
Hayward, Caroline http://orcid.org/0000-0002-9405-9550
Hicks, Andrew A. http://orcid.org/0000-0001-6320-0411
Hofer, Edith
Holm, Hilma
Huang, Wei
Hutri-Kähönen, Nina
Hwang, Shih-Jen
Ikram, M. Arfan http://orcid.org/0000-0003-0372-8585
Lewis, Raychel M.
Ingelsson, Erik http://orcid.org/0000-0003-2256-6972
Jakobsdottir, Johanna
Jonsdottir, Ingileif http://orcid.org/0000-0001-8339-150X
Jonsson, Helgi
Joshi, Peter K. http://orcid.org/0000-0002-6361-5059
Josyula, Navya Shilpa http://orcid.org/0000-0003-2782-8812
Jung, Bettina
Kähönen, Mika
Kamatani, Yoichiro http://orcid.org/0000-0001-8748-5597
Kanai, Masahiro http://orcid.org/0000-0001-5165-4408
Kerr, Shona M.
Kiess, Wieland
Kleber, Marcus E. http://orcid.org/0000-0003-0663-7275
Koenig, Wolfgang http://orcid.org/0000-0002-2064-9603
Kooner, Jaspal S.
Körner, Antje
Kovacs, Peter http://orcid.org/0000-0002-0290-5423
Krämer, Bernhard K.
Kronenberg, Florian http://orcid.org/0000-0003-2229-1120
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La Bianca, Martina
Lange, Leslie A.
Lehne, Benjamin
Lehtimäki, Terho
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Loeffler, Markus
Loos, Ruth J. F. http://orcid.org/0000-0002-8532-5087
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Magi, Reedik
Mahajan, Anubha http://orcid.org/0000-0001-5585-3420
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März, Winfried
Mascalzoni, Deborah
Matsuda, Koichi
Meisinger, Christa
Meitinger, Thomas
Metspalu, Andres http://orcid.org/0000-0002-3718-796X
Milaneschi, Yuri
O’Donnell, Christopher J.
Wilson, Otis D.
Gaziano, J. Michael
Mishra, Pashupati P.
Mohlke, Karen L. http://orcid.org/0000-0001-6721-153X
Mononen, Nina
Montgomery, Grant W. http://orcid.org/0000-0002-4140-8139
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Müller-Nurasyid, Martina http://orcid.org/0000-0003-3793-5910
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Nalls, Mike A.
Nauck, Matthias
Nikus, Kjell
Ning, Boting
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Poulain, Tanja
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Rettig, Rainer
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Cifkova, Renata
Rueedi, Rico
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Stumvoll, Michael
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Thiery, Joachim
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Waldenberger, Melanie
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Scholz, Markus http://orcid.org/0000-0002-4059-1779
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Teumer, Alexander
Pattaro, Cristian
Woodward, Owen M. http://orcid.org/0000-0001-9514-2180
Vitart, Veronique http://orcid.org/0000-0002-4991-3797
Köttgen, Anna http://orcid.org/0000-0002-4671-3714
,
,
Funding for this research was provided by:
U.S. Department of Health & Human Services | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases (R01AR073178-01A1)
Deutsche Forschungsgemeinschaft (KO 3598/4-1, CRC 1140, project number 246781735)
EC | European Regional Development Fund
National Health and Medical Research Council (NHMRC) Fellowship Schemes
Dutch Science Organization
American Heart Association (Postdoctoral Fellowship (17POST3650016))
Nederlandse Organisatie voor Wetenschappelijk Onderzoek (016.186.125)
U.S. Department of Health & Human Services | NIH | National Institute of General Medical Sciences (U54GM115428)
Article History
Received: 17 January 2019
Accepted: 27 August 2019
First Online: 2 October 2019
Competing interests
: D.O.M.-K. works as a part-time clinical research consultant for METABOLON. B.W.J.H.P. has received research funding (unrelated to the work reported in this article) from Jansen Research and Boehringer Ingelheim. K.B.S is full-time employee of GlaxoSmithKline. G.S., D.F.G., I.J., H.H., P.S., U.T. and K.Stefansson are full time employees of deCODE genetics and Amgen. A.Y.C. is an employee of Merck & Co. W.Koenig received modest consultation fees for advisory board meetings from Amgen, DalCor Pharmaceuticals, Kowa, Novartis, Pfizer and Sanofi, and modest personal fees for lectures from Amgen, AstraZeneca, Novartis, Pfizer and Sanofi. D.C. is scientific consultant for Bio4Dreams. W.M. is employed by Synlab Services GmbH and holds shares of Synlab Holding Deutschland GmbH. M.A.N.’s participation in this project is supported by a consulting contract between Data Tecnica International, the National Institute on Aging and NIH, and consults or has consulted during this time for Lysosomal Therapeutics, Neuron23, Illumina, the Michael J. Fox Foundation and the University of California Healthcare. O.P. is an owner of Gen-info. K.Ho has disclosed a research and financial relationship with Sanofi Genzyme. B.M.P. serves on the Data and Safety Monitoring Board of a clinical trial funded by the manufacturer (Zoll Lifecor) and on the Steering Committee of the Yale Open Data Access Project funded by Johnson & Johnson. A.S.B. received grants from MSD, Pfizer, Novartis, Biogen and Bioverativ and personal fees from Novartis. F.R. is a scientific consultant for ePhood. M.Scholz consults for and received grant support not related to this project from Merck Serono. A.Köttgen received grant support not related to this project from Grünenthal. The other authors declare no competing interests.