Sörmann, Janina http://orcid.org/0000-0002-3288-6681
Schewe, Marcus http://orcid.org/0000-0002-6192-5651
Proks, Peter
Jouen-Tachoire, Thibault http://orcid.org/0000-0001-5867-994X
Rao, Shanlin http://orcid.org/0000-0003-4892-5523
Riel, Elena B. http://orcid.org/0000-0003-3227-9344
Agre, Katherine E.
Begtrup, Amber http://orcid.org/0000-0002-2872-3281
Dean, John
Descartes, Maria
Fischer, Jan
Gardham, Alice
Lahner, Carrie
Mark, Paul R. http://orcid.org/0000-0002-1020-888X
Muppidi, Srikanth
Pichurin, Pavel N.
Porrmann, Joseph
Schallner, Jens
Smith, Kirstin
Straub, Volker http://orcid.org/0000-0001-9046-3540
Vasudevan, Pradeep
Willaert, Rebecca
Carpenter, Elisabeth P.
Rödström, Karin E. J.
Hahn, Michael G.
Müller, Thomas http://orcid.org/0000-0001-9017-4781
Baukrowitz, Thomas
Hurles, Matthew E. http://orcid.org/0000-0002-2333-7015
Wright, Caroline F. http://orcid.org/0000-0003-2958-5076
Tucker, Stephen J. http://orcid.org/0000-0001-8996-2000
Funding for this research was provided by:
RCUK | Biotechnology and Biological Sciences Research Council (BB/S008608/1, BB/T002018/1, BB/T002018/1)
Wellcome Trust (WT098051, WT084655MA, WT084655MA, 102161/B/13/Z, WT098051, WT098051)
Deutsche Forschungsgemeinschaft (SCHE 2112/1-2, SCHE 2112/1-2, BA 1793/6-2)
Article History
Received: 5 August 2021
Accepted: 9 August 2022
First Online: 4 October 2022
Ethical approval
: Ethical approval for the original study<sup>28</sup> was provided by the UK Research Ethics Committee (10/H0305/83, granted by the Cambridge South REC, and GEN/284/12, granted by the Republic of Ireland REC). This includes informed consent for all human participants.
: M.G.H. and T.M. are employees of Bayer AG and are involved in the development of TASK-1 inhibitors for the treatment of sleep apnea. M.E.H. is scientific director of Congenica. A.B. and R.W. are employees of GeneDx, Inc. The other authors declare no conflicts of interest.