Darabedian, Narek
Ji, Wenzhi
Fan, Mengyang
Lin, Shan
Seo, Hyuk-Soo http://orcid.org/0000-0003-0646-2102
Vinogradova, Ekaterina V.
Yaron, Tomer M.
Mills, Evanna L.
Xiao, Haopeng
Senkane, Kristine
Huntsman, Emily M.
Johnson, Jared L. http://orcid.org/0000-0003-1802-6527
Che, Jianwei http://orcid.org/0000-0003-4956-4811
Cantley, Lewis C. http://orcid.org/0000-0002-1298-7653
Cravatt, Benjamin F. http://orcid.org/0000-0001-5330-3492
Dhe-Paganon, Sirano http://orcid.org/0000-0003-0824-5929
Stegmaier, Kimberly http://orcid.org/0000-0003-0218-7895
Zhang, Tinghu
Gray, Nathanael S. http://orcid.org/0000-0001-5354-7403
Chouchani, Edward T. http://orcid.org/0000-0002-9776-8790
Funding for this research was provided by:
Foundation for the National Institutes of Health (CA259739-01)
Article History
Received: 18 April 2022
Accepted: 30 January 2023
First Online: 23 February 2023
Competing interests
: N.S.G. is a founder, science advisory board member (SAB) and equity holder in Syros, C4, Allorion, Lighthorse, Voronoi, Inception, Matchpoint, CobroVentures, GSK, Shenandoah (board member), Larkspur (board member) and Soltego (board member). The Gray lab receives or has received research funding from Novartis, Takeda, Astellas, Taiho, Jansen, Kinogen, Arbella, Deerfield, Springworks, Interline and Sanofi. E.T.C. is a founder, board member and equity holder in Matchpoint Therapeutics and Aevum Therapeutics. T.Z. and J.C. are founders, equity holders and consultants in Matchpoint Therapeutics. J.C. is a scientific co-founder M3 Bioinformatics & Technology Inc., and consultant and equity holder for Soltego and Allorion. K. Stegmaier has funding from Novartis Institute of Biomedical Research and Kronos Bio, consults for and has stock options in Auron Therapeutics and previously consulted for Kronos Bio and AstraZeneca. T.M.Y. is a co-founder, stockholder and on the board of directors of DESTROKE, Inc. T.Z., W.J., N.D., N.S.G., J.C. and E.T.C. are inventors on a patent for CK inhibitors WO 2022/087433 A8. All other authors declare no potential conflict of interest. B.F.C. is a founder and scientific advisor to Vividion Therapeutics.