LaFleur, Martin W.
Lemmen, Ashlyn M.
Streeter, Ivy S. L. http://orcid.org/0000-0003-0729-1042
Nguyen, Thao H.
Milling, Lauren E.
Derosia, Nicole M.
Hoffman, Zachary M.
Gillis, Jacob E.
Tjokrosurjo, Qin
Markson, Samuel C. http://orcid.org/0000-0001-9053-9867
Huang, Amy Y. http://orcid.org/0000-0002-6646-6503
Anekal, Praju V.
Montero Llopis, Paula
Haining, W. Nicholas
Doench, John G. http://orcid.org/0000-0002-3707-9889
Sharpe, Arlene H. http://orcid.org/0000-0002-9736-2109
Funding for this research was provided by:
U.S. Department of Health & Human Services | NIH | National Institute of Allergy and Infectious Diseases (U19AI133524, P01 AI108545, U19AI133524)
U.S. Department of Health & Human Services | NIH | National Cancer Institute (U54 CA225088)
Article History
Received: 7 October 2022
Accepted: 20 October 2023
First Online: 27 November 2023
Competing interests
: A.H.S. has patents/pending royalties on the PD-1 pathway from Roche and Novartis. A.H.S. is on advisory boards for Elpiscience, Selecta, Bicara, Monopteros, Fibrogen, Alixia, IOME, Corner Therapeutics, GlaxoSmithKline, Amgen and Janssen. A.H.S. has received research funding from Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc., Rahway, NJ, USA related to this project and Vertex, Moderna, Quark/Iome, AbbVie and Erasca unrelated to this project. J.G.D. consults for Microsoft Research, Abata Therapeutics, Servier, Maze Therapeutics, BioNTech, Sangamo and Pfizer. J.G.D. consults for and has equity in Tango Therapeutics. J.G.D. serves as a paid scientific advisor to the Laboratory for Genomics Research, funded in part by GlaxoSmithKline. J.G.D. receives funding support from the Functional Genomics Consortium: AbbVie, Bristol Myers Squibb, Janssen, Vir Biotechnology, and Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc., Rahway, NJ, USA. J.G.D.’s interests were reviewed and are managed by the Broad Institute in accordance with its conflict-of-interest policies. W.N.H. is an employee of and holds equity in Arsenal Biosciences. The remaining authors declare no competing interests.