Funding for this research was provided by:
U.S. Environmental Protection Agency (R835873)
Wellcome Trust (209376/Z/17/Z)
Received: 29 July 2019
Accepted: 26 November 2019
First Online: 13 January 2020
: M.E. reports a charitable grant from AstraZeneca Young Health Programme, and personal fees from Prudential, Scor and Third Bridge, all outside the submitted work; all other authors declare no competing interests.