Krystal, Andrew D. http://orcid.org/0000-0002-6702-781X
Pizzagalli, Diego A. http://orcid.org/0000-0002-7772-1143
Smoski, Moria
Mathew, Sanjay J.
Nurnberger, John Jr
Lisanby, Sarah H.
Iosifescu, Dan
Murrough, James W.
Yang, Hongqiu
Weiner, Richard D.
Calabrese, Joseph R. http://orcid.org/0000-0003-4647-8571
Sanacora, Gerard
Hermes, Gretchen
Keefe, Richard S. E.
Song, Allen
Goodman, Wayne
Szabo, Steven T.
Whitton, Alexis E. http://orcid.org/0000-0002-7944-2172
Gao, Keming
Potter, William Z.
Funding for this research was provided by:
U.S. Department of Health & Human Services | NIH | National Institute of Mental Health (HHS-N271-2012-000006-I, R37 MH068376)
Article History
Received: 5 May 2019
Accepted: 20 February 2020
First Online: 30 March 2020
Competing interests
: A.D.K. has been a consultant for Adare, Eisai, Ferring, Galderma, Idorsia, Jazz, Janssen, Takeda, Merck, Neurocrine, Pernix, Physician’s Seal, Evecxia and Sage Research and received support from the NIH, the Ray and Dagmar Dolby Family Fund, Janssen, Jazz. Axsome and Reveal Biosensors. D.A.P. has consulted for Akili Interactive Labs, BlackThorn Therapeutics, Boehringer Ingelheim, Compass Pathway, Otsuka Pharmaceuticals, Posit Science and Takeda Pharmaceuticals and received honoraria from Alkermes. D.A.P. has a financial interest in BlackThorn Therapeutics, which has licensed the copyright to the PRT through Harvard University. The interests of D.A.P. were reviewed and are managed by McLean Hospital and Partners HealthCare in accordance with their conflict-of-interest policies. No funding from these entities was used to support the current work, and all views expressed are solely those of the authors. S.J.M. has been a consultant for Allergan, Alkermes, Greenwich Biosciences, Clexio Biosciences, Intra-Cellular Therapies, Janssen, Perception Neuroscience, Sage Therapeutics, Signant Health and Seelos Therapeutics and received research support from Biohaven, Janssen, the NIH, NeuroRx and VistaGen Therapeutics, drug from Biohaven for NIMH-funded study and support from the Michael E. Debakey VA Medical Center (Houston, TX) for use of resources and facilities. G.S. has consulted for Allergan, Alkermes, AstraZeneca, Avanier Pharmaceuticals, Axsome Therapeutics, Biohaven Pharmaceuticals, Boehringer Ingelheim, Bristol-Myers Squibb, Clexio Biosciences, EMA-Wellness, Hoffman La-Roche, Intra-Cellular Therapies, Janssen, Merck, Naurex, Navitor Pharmaceuticals, Novartis, Noven Pharmaceuticals, Otsuka, Praxis Therapeutics, Sage Pharmaceuticals, Servier Pharmaceuticals, Taisho Pharmaceuticals, Teva, Valeant and Vistagen Therapeutics and received research funding from AstraZeneca, Bristol-Myers Squibb, Eli Lilly, Johnson & Johnson, Hoffman La-Roche, Merck, Naurex and Servier. G.S. has equity interests in Biohaven Pharmaceuticals and receives patent royalties from Biohaven. J.W.M. has consulted for Boehringer Ingelheim, Sage Therapeutics, Novartis, Allergan, Fortress Biotech, Janssen Research and Development, Medavante-Prophase and Global Medical Education (GME) and received research support from Avanir Pharmaceuticals. R.S.E.K. has consulted for or been a speaker or advisory board member for Abbvie, Acadia, Aeglea, Akebia, Akili, Alkermes, Allergan, ArmaGen, Astellas, Avanir, Axovant, Biogen, Boehringer Ingelheim, Cerecor, CoMentis, Critical Path Institute, FORUM, Gammon Howard & Zeszotarski, Global Medical Education (GME), GW Pharmaceuticals, Intracellular Therapeutics, Janssen, Kempharm, Lundbeck, Lysogene, MedScape, Mentis Cura, Merck, Merrakris Therapetics, Minerva Neurosciences, Mitsubishi, Montana State University, Monteris, Moscow Research Institute of Psychiatry, Neuralstem, Neuronix, Novartis, the New York State Office of Mental Health, Orygen, Otsuka, Paradigm Testing, Percept Solutions, Pfizer, Pharm-Olam, Regenix Bio, Reviva, Roche, Sangamo, Sanofi, SOBI, Six Degrees Medical, Sunovion, Takeda, Targacept, Teague Rotenstreich Stanaland Fox & Holt, Thrombosis Research Institute, the University of Moscow, the University of Southern California, the University of Texas Southwestern Medical Center, WebMD and Wilson Therapeutics. R.S.E.K. has received research funding from the National Institute of Mental Health and Boehringer Ingelheim and royalties from Versions of the BAC testing battery, the MATRICS Battery (BACS Symbol Coding) and the Virtual Reality Functional Capacity Assessment Tool (VRFCAT). R.S.E.K. is a shareholder in VeraSci and Sengenix. S.H.L. contributed to this article while at Duke University, before joining the National Institute of Mental Health. The views expressed are her own and do not necessarily represent the views of the National Institutes of Health or the US government. S.H.L. is a co-inventor on a patent for TMS Technology, unrelated to this manuscript. J.N. has received research funding from Janssen and Assurex. A.S. has received research support from the NIH and GE Healthcare. W.G. has consulted for Biohaven Pharmaceuticals and received research funding from the NIH, the Simons Foundation and Biohaven Pharmaceuticals Device Donation: Medtronic. S.T.S. has consulted for Otsuka Pharmaceuticals, Neurocrine Biosciences, Jazz, Teva and the Centers of Psychiatric Excellence and Continuous Precision Medicine and received research support from Otsuka Pharmaceuticals and Veterans’ Affairs grant IK2CX001397. K.G. has been on the advisory board of Sunovion and Otsuka Pharmaceuticals and received research funding from AstraZeneca, the Cleveland Foundation and the Brain and Behavioral Research Foundation. K.G. has been a speaker for AstraZeneca, Pfizer and Sunovion. W.Z.P. has been on the advisory board and/or consulted for Takeda, Lilly, Praxis, Astellas, Otsuka and Noven. W.Z.P. has been on the DSMB for Agene-Bio and has stock ownership in Merck.