Ogishi, Masato http://orcid.org/0000-0003-2421-7389
Yang, Rui
Aytekin, Caner http://orcid.org/0000-0002-2921-5270
Langlais, David http://orcid.org/0000-0003-4429-0110
Bourgey, Mathieu http://orcid.org/0000-0002-8432-834X
Khan, Taushif
Ali, Fatima Al
Rahman, Mahbuba
Delmonte, Ottavia M.
Chrabieh, Maya
Zhang, Peng http://orcid.org/0000-0002-6129-567X
Gruber, Conor
Pelham, Simon J. http://orcid.org/0000-0002-3119-662X
Spaan, András N. http://orcid.org/0000-0001-5981-7259
Rosain, Jérémie http://orcid.org/0000-0002-2822-161X
Lei, Wei-Te
Drutman, Scott
Hellmann, Matthew D. http://orcid.org/0000-0002-2670-9777
Callahan, Margaret K. http://orcid.org/0000-0002-9087-0012
Adamow, Matthew http://orcid.org/0000-0002-7709-0126
Wong, Phillip http://orcid.org/0000-0002-6360-849X
Wolchok, Jedd D. http://orcid.org/0000-0001-6718-2222
Rao, Geetha
Ma, Cindy S. http://orcid.org/0000-0001-5387-8413
Nakajima, Yuka http://orcid.org/0000-0002-7357-2910
Yaguchi, Tomonori
Chamoto, Kenji
Williams, Samuel C.
Emile, Jean-Francois http://orcid.org/0000-0002-6073-4466
Rozenberg, Flore
Glickman, Michael S. http://orcid.org/0000-0001-7918-5164
Rapaport, Franck
Kerner, Gaspard
Allington, Garrett
Tezcan, Ilhan
Cagdas, Deniz http://orcid.org/0000-0003-2213-4627
Hosnut, Ferda O.
Dogu, Figen
Ikinciogullari, Aydan
Rao, V. Koneti
Kainulainen, Leena
Béziat, Vivien http://orcid.org/0000-0002-4020-824X
Bustamante, Jacinta
Vilarinho, Silvia http://orcid.org/0000-0002-2099-4212
Lifton, Richard P.
Boisson, Bertrand http://orcid.org/0000-0001-5240-3555
Abel, Laurent
Bogunovic, Dusan
Marr, Nico http://orcid.org/0000-0002-1927-7072
Notarangelo, Luigi D. http://orcid.org/0000-0002-8335-0262
Tangye, Stuart G. http://orcid.org/0000-0002-5360-5180
Honjo, Tasuku http://orcid.org/0000-0003-2300-3928
Gros, Philippe http://orcid.org/0000-0002-0114-1978
Boisson-Dupuis, Stéphanie http://orcid.org/0000-0002-7115-116X
Casanova, Jean-Laurent http://orcid.org/0000-0002-7782-4169
Funding for this research was provided by:
Division of Intramural Research, National Institute of Allergy and Infectious Diseases (R37AI095983, U19AI111143, U19AI142737)
U.S. Department of Health & Human Services | National Institutes of Health (UL1TR001866)
U.S. Department of Health & Human Services | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (K08 DK113109)
Article History
Received: 2 November 2020
Accepted: 6 May 2021
First Online: 28 June 2021
Competing interests
: M.S.G. has received consulting fees from Takeda, serves on the Scientific Advisory Board (SAB) of Vedanta Biosciences and receives consulting fees and equity and serves on the SAB of the Pandemic Response Lab of New York City. J.D.W. is a consultant for: Adaptive Biotech; Amgen; Apricity; Ascentage Pharma; Arsenal IO; Astellas; AstraZeneca; Bayer; Beigene; Boehringer Ingelheim; Bristol Myers Squibb; Celgene; Chugai; Daiichi Sankyo; Dragonfly; Eli Lilly; Elucida; F Star; Georgiamune; Idera; Imvaq; Kyowa Hakko Kirin; Linneaus; Maverick Therapeutics; Merck; Neon Therapeutics; Polynoma; Psioxus; Recepta; Takara Bio; Trieza; Truvax; Trishula; Sellas; Serametrix; Surface Oncology; Syndax; Syntalogic; and Werewolf Therapeutics. J.D.W. receives research support grants from: Bristol Myers Squibb and Sephora. J.D.W. has equity in: Tizona Pharmaceuticals; Adaptive Biotechnologies; Imvaq; Beigene; Linneaus; Apricity; Arsenal IO; and Georgiamune. M.D.H. reports grants from BMS; personal fees from Achilles, Arcus, AstraZeneca, Blueprint, BMS, Eli Lilly, Genentech/Roche, Genzyme/Sanofi, Janssen, Immunai, Instil Bio, Mana Therapeutics, Merck, Mirati, Natera, Pact Pharma, Shattuck Labs and Regeneron; and equity options from Factorial, Immunai, Shattuck Labs and Arcus. A patent filed by Memorial Sloan Kettering related to the use of tumor mutational burden to predict response to immunotherapy (PCT/US2015/062208) is pending and licensed by PGDx. S.D. became employed at Regeneron Pharmaceuticals after his contributions to this work. All other authors declare no competing interests.