Bhatt, Deepak L. http://orcid.org/0000-0002-1278-6245
Bays, Harold E.
Miller, Michael
Cain, James E. III
Wasilewska, Katarzyna
Andrawis, Nabil S.
Parli, Teresa http://orcid.org/0000-0001-9540-8436
Feng, Shibao
Sterling, Lulu
Tseng, Leo
Hartsfield, Cynthia L.
Agollah, Germaine D.
Mansbach, Hank
Kastelein, John J. P.
,
Funding for this research was provided by:
89bio, Inc.
Article History
Received: 29 January 2023
Accepted: 30 May 2023
First Online: 24 June 2023
Change Date: 4 March 2024
Change Type: Correction
Change Details: A Correction to this paper has been published:
Change Details: https://doi.org/10.1038/s41591-024-02890-2
Competing interests
: D.L.B. serves on the following Advisory Boards—AngioWave, Bayer, Boehringer Ingelheim, Cardax, CellProthera, Cereno Scientific, Elsevier Practice Update Cardiology, High Enroll, Janssen, Level Ex, McKinsey, Medscape Cardiology, Merck, MyoKardia, NirvaMed, Novo Nordisk, PhaseBio, PLx Pharma, Regado Biosciences and Stasys. D.L.B. is on the Board of Directors of the following—Angiowave (stock options), Boston VA Research Institute, Bristol Myers Squibb (stock), DRS.LINQ (stock options), High Enroll (stock), Society of Cardiovascular Patient Care and TobeSoft. D.L.B. is the Inaugural Chair of the American Heart Association Quality Oversight Committee. D.L.B. is a Consultant at Broadview Ventures and Hims. D.L.B. is on the following Data Monitoring Committees—Acesion Pharma, Assistance Publique-Hôpitaux de Paris, Baim Institute for Clinical Research (formerly Harvard Clinical Research Institute, for the PORTICO trial, funded by St. Jude Medical, now Abbott), Boston Scientific (Chair, PEITHO trial), Cleveland Clinic (including for the ExCEED trial, funded by Edwards), Contego Medical (Chair, PERFORMANCE 2), Duke Clinical Research Institute, Mayo Clinic, Mount Sinai School of Medicine (for the ENVISAGE trial, funded by Daiichi Sankyo; for the ABILITY-DM trial, funded by Concept Medical), Novartis, Population Health Research Institute; Rutgers University (for the NIH-funded MINT Trial). D.L.B. has received the following Honoraria—American College of Cardiology (Senior Associate Editor, Clinical Trials and News, ACC.org; Chair, ACC Accreditation Oversight Committee), Arnold and Porter law firm (work related to Sanofi/Bristol Myers Squibb clopidogrel litigation), Baim Institute for Clinical Research (formerly Harvard Clinical Research Institute; RE-DUAL PCI clinical trial steering committee funded by Boehringer Ingelheim; AEGIS-II executive committee funded by CSL Behring), Belvoir Publications (Editor-in-Chief, Harvard Heart Letter), Canadian Medical and Surgical Knowledge Translation Research Group (clinical trial steering committees), Cowen and Company, Duke Clinical Research Institute (clinical trial steering committees, including for the PRONOUNCE trial, funded by Ferring Pharmaceuticals), HMP Global (Editor-in-Chief, Journal of Invasive Cardiology), Journal of the American College of Cardiology (Guest Editor; Associate Editor), K2P (Co-Chair, interdisciplinary curriculum), Level Ex, Medtelligence/ReachMD (CME steering committees), MJH Life Sciences, Oakstone CME (Course Director, Comprehensive Review of Interventional Cardiology), Piper Sandler, Population Health Research Institute (for the COMPASS operations committee, publications committee, steering committee and USA national co-leader, funded by Bayer), Slack Publications (Chief Medical Editor, Cardiology Today’s Intervention), Society of Cardiovascular Patient Care (Secretary/Treasurer), WebMD (CME steering committees) and Wiley (steering committee). Additional disclosures for D.L.B. include <i>Clinical Cardiology</i> (Deputy Editor), NCDR-ACTION Registry Steering Committee (Chair), VA CART Research and Publications Committee (Chair); Patent—Sotagliflozin (named on a patent for sotagliflozin assigned to Brigham and Women’s Hospital who assigned to Lexicon; neither I nor Brigham and Women’s Hospital receive any income from this patent); Research Funding—Abbott, Acesion Pharma, Afimmune, Aker Biomarine, Amarin, Amgen, AstraZeneca, Bayer, Beren, Boehringer Ingelheim, Boston Scientific, Bristol Myers Squibb, Cardax, CellProthera, Cereno Scientific, Chiesi, CinCor, Cleerly, CSL Behring, Eisai, Ethicon, Faraday Pharmaceuticals, Ferring Pharmaceuticals, Forest Laboratories, Fractyl, Garmin, HLS Therapeutics, Idorsia, Ironwood, Ischemix, Janssen, Javelin, Lexicon, Lilly, Medtronic, Merck, Moderna, MyoKardia, NirvaMed, Novartis, Novo Nordisk, Owkin, Pfizer, PhaseBio, PLx Pharma, Recardio, Regeneron, Reid Hoffman Foundation, Roche, Sanofi, Stasys, Synaptic, The Medicines Company, Youngene and 89bio Inc.; Royalties—Elsevier (Editor, Braunwald’s Heart Disease); Site Co-Investigator—Abbott, Biotronik, Boston Scientific, CSI, Endotronix, St. Jude Medical (now Abbott), Philips, SpectraWAVE, Svelte, Vascular Solutions; Trustee—American College of Cardiology; Unfunded Research—FlowCo and Takeda. H.E.B. reports the following competing interests: Consulting Fee—89bio Inc., Amgen, Esperion; Research Support—89bio Inc., Akcea, Allergan, Alon Medtech/Epitomee, Amgen, Anji Pharma, AstraZeneca, Axsome, BioHaven, Bionime, Boehringer Ingelheim, CinCor, Civi, CSL Behring, Eli Lilly, Esperion, Evidera, Gan and Lee, Home Access, Lexicon, Matinas, Merck, Metavant, Novartis, Novo Nordisk, Pfizer, Regeneron, Sanofi, Satsuma, Selecta and TIMI; Speaker Bureau; E.M.M.: Advisory Board Member and Consulting fees—Amarin and 89bio Inc. J.E.C.III: has no disclosures to report. K.W. has no disclosures to report. N.S.A. has no disclosures to report. The following are employees of 89bio Inc., and may own stock: T.P., S.F., L.S., L.T., C.L.H., G.D.A. and H.M. J.J.P.K. reports the following competing interests: Consulting Fee—CIVI Biotechnology, Cincor, CSL Behring, Draupnir, Esperion, Inversago, Madrigal Pharmaceuticals, North Sea Therapeutics, Novartis, Regeneron, RegenXBio, Scribe therapeutics, Staten Biotech, and 89bio Inc.; Omeicos part-time employee: NewAmsterdam Pharma.