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Article History
Received: 25 May 2023
Accepted: 2 January 2024
First Online: 19 February 2024
Competing interests
: N.S.A.-H. is an employee and equity holder of 23andMe; serves as a scientific advisory board member for Allelica, Inc; received personal fees from Genentech Inc, Allelica Inc, and 23andMe; received research funding from Akcea Therapeutics; and was previously employed by Regeneron Pharmaceuticals. E.E.K. received personal fees from Illumina Inc, 23andMe and Regeneron Pharmaceuticals and serves as a scientific advisory board member for Encompass Bioscience, Foresite Labs and Galateo Bio. J.N.H. has equity in Camp4 Therapeutics and has been a consultant to Amgen, AstraZeneca, Cytokinetics, PepGen, Pfizer and Tenaya Therapeutics and is the founder of Ikaika Therapeutics. J.F.P. is a paid consultant for Natera Inc. A. Khera. is an employee of Verve Therapeutics. N.L. received personal fees from Illumina Inc and is a scientific advisory board member for FYR Diagnostics. J.F.P. is a consultant for Myome. D.V. is a consultant for Illumina and has grant support from GeneDx. T.L.W. has grant funding from Gilead Sciences, Inc. The other authors declare no competing interests.