Received: 9 January 2020
Accepted: 21 November 2020
First Online: 11 January 2021
: The first part of this study used existing and publicly available genomic datasets of families with ASD from the Simons Simplex Collection (SSC) and Simons Powering Autism Research for Knowledge (SPARK). Collection of SSC samples was approved and monitored by the institutional review board of Columbia University Medical Center. SPARK samples were collected under a centralized review board protocol (Western IRB Protocol no. 20151664). The second part of the study generated and analyzed genomic data on de-identified postmortem human specimens obtained from brain tissue banks, including the AutismBrainNet, the Lieber Institute for Brain Development, the Oxford Brain Bank and the University of Maryland Brain and Tissue Bank through the National Institutes of Health Neurobiobank. This study did not engage human subjects or collect their identifiable data; rather, the individual tissue banks have their own approval and consent process. Our study was approved by the institutional review board of Boston Children’s Hospital.
: The authors declare no competing interests.