Michallek, Florian
Nakamura, Satoshi
Ota, Hideki
Ogawa, Ryo
Shizuka, Takehito
Nakashima, Hitoshi
Wang, Yi-Ning
Ito, Tatsuro
Sakuma, Hajime
Dewey, Marc
Kitagawa, Kakuya
Funding for this research was provided by:
Deutsche Forschungsgemeinschaft (392304398, 392304398)
Charité - Universitätsmedizin Berlin
Article History
Received: 3 November 2021
Accepted: 17 March 2022
First Online: 24 March 2022
Competing interests
: The study protocol is published in the UMIN-Clinical Trial Registry under the registration number UMIN000016353, has received institutional review board approval (Clinical Research Ethics Review Committee of Mie University Hospital), and complied with the Declaration of Helsinki. Written informed consent from all participants has been obtained. The AMPLIFiED study was funded by Bayer Japan. Florian Michallek: FM holds a United States patent (USPTO: 10,991,109, Patent 2021) on fractal analysis of perfusion imaging and has filed a patent application on the same topic at the European Patent Office (PCT/EP2016/071551), each together with MD. FM receives grant support from the German Research Foundation (DFG, grant number Ml 2272/1-1 [392304398]), which covers 50% of his position. Marc Dewey: MD holds a United States patent (USPTO: 10,991,109, Patent 2021) on fractal analysis of perfusion imaging and has filed a patent application on the same topic at the European Patent Office (PCT/EP2016/071551), each together with FM. MD receives grant support from the German Research Foundation for this project (DFG, grant number DE 1361/18-1 [392304398]). MD has received grant support from the FP7 Program of the European Commission for the randomized multicenter DISCHARGE trial (603266-2, HEALTH-2012.2.4.-2). He also received grant support from German Research Foundation (DFG) in the Heisenberg Program (DE 1361/14-1), graduate program on quantitative biomedical imaging (BIOQIC, GRK 2260/1), the Priority Programme Radiomics for the investigation of coronary plaque and coronary flow (DE 1361/19-1 [428222922] and 20-1 [428223139] in SPP 2177/1). He also received funding from the Berlin University Alliance (GC_SC_PC 27) and from the Digital Health Accelerator of the Berlin Institute of Health. MD is European Society of Radiology (ESR) Research Chair (2019–2022) and the opinions expressed in this article are the author’s own and do not represent the view of ESR. Per the guiding principles of ESR, the work as Research Chair is on a voluntary basis and only remuneration of travel expenses occurs. Prof. Dewey is also the editor of Cardiac CT, published by Springer Nature, and offers hands-on courses on CT imaging (ExternalRef removed). Institutional master research agreements exist with Siemens, General Electric, Philips, and Canon. The terms of these arrangements are managed by the legal department of Charité – Universitätsmedizin Berlin. Hajime Sakuma: HS has received support from Daiichi Sankyo Co. Ltd, Fuji Pharma Co. Ltd., FUJIFILM RI Pharma Co. Ltd., Eisai Co. Ltd. Kakuya Kitagawa: KK has received support from Siemens Japan. SN, HO, RO, TS, HN, YW and TI do not declare competing interests relevant to this manuscript.