Khurshid, Shaan
Reeder, Christopher
Harrington, Lia X.
Singh, Pulkit
Sarma, Gopal
Friedman, Samuel F.
Di Achille, Paolo http://orcid.org/0000-0001-9256-0678
Diamant, Nathaniel http://orcid.org/0000-0002-1738-304X
Cunningham, Jonathan W. http://orcid.org/0000-0003-4481-7867
Turner, Ashby C.
Lau, Emily S.
Haimovich, Julian S.
Al-Alusi, Mostafa A.
Wang, Xin
Klarqvist, Marcus D. R. http://orcid.org/0000-0001-7630-2708
Ashburner, Jeffrey M.
Diedrich, Christian
Ghadessi, Mercedeh
Mielke, Johanna
Eilken, Hanna M.
McElhinney, Alice
Derix, Andrea
Atlas, Steven J.
Ellinor, Patrick T. http://orcid.org/0000-0002-2067-0533
Philippakis, Anthony A.
Anderson, Christopher D.
Ho, Jennifer E. http://orcid.org/0000-0002-7987-4768
Batra, Puneet http://orcid.org/0000-0001-6822-0593
Lubitz, Steven A. http://orcid.org/0000-0002-9599-4866
Funding for this research was provided by:
U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute (1R01HL139731, T32HL007208, R38HL150212, K01HL148506, 1R01HL092577, R01HL128914, K24HL105780, R01NS103924, U01NS069673, R01HL134893, R01HL140224, K24HL153669)
American Heart Association (18SFRN34250007, 18SFRN34250007, 18SFRN34250007, 18SFRN34110082, 18SFRN34250007, 21SFRN812095)
U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute
U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute
U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute
U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute
U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute
U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute
Fondation Leducq (14CVD01)
U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute
U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute
U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute
U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute
U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute
Article History
Received: 26 May 2021
Accepted: 9 March 2022
First Online: 8 April 2022
Competing interests
: The authors declare the following financial and non-financial interests: A.A.P. receives sponsored research support from Bayer AG, IBM, Intel, and Verily. He has also received consulted fees from Novartis and Rakuten. He is a Venture Partner at GV and is compensated for this work. J.E.H. receives sponsored research support from Bayer AG and Gilead Sciences. J.E.H. has received research supplies from EcoNugenics. S.F.F. receives sponsored research support from Bayer AG and IBM. C.D.A. receives sponsored research support from Bayer AG and has consulted for ApoPharma and Invitae. P.B. receives sponsored research support from Bayer AG and IBM, and consults for Novartis. S.A.L. receives sponsored research support from Bristol Myers Squibb/Pfizer, Bayer AG, Boehringer Ingelheim, and Fitbit, has consulted for Bristol Myers Squibb/Pfizer and Bayer AG, and participates in a research collaboration with IBM. P.T.E. receives sponsored research support from Bayer AG and IBM Research and he has consulted for Bayer AG, Novartis, MyoKardia, and Quest Diagnostics. S.J.A. receives sponsored research support from Bristol Myers Squibb/Pfizer and has consulted for Bristol Myers Squibb/Pfizer and Fitbit. J.M.A. has received sponsored research support from Bristol Myers Squibb/Pfizer. C.D., J.M., H.M.E., A.D., and M.G. are employees of Bayer AG. The remaining authors declare no competing interests.